Product Information
HYDROQUINONE 4% CREAM is a generic product labeled by Acella Pharmaceuticals, LLC, priced at $0.5130 per GM under NDC 42192015101. Its NADAC has been published 434 times since Mar 14, 2018.
Strength
40 mg/g
Manufacturer
Acella Pharmaceuticals, LLCNDC
42192015101
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
HYDROQUINONEApproval Type
Unapproved
On Market Since
9/10/2014
Pharmacological Classes
Price Statistics
The NADAC for HYDROQUINONE 4% CREAM has been published 434 times since Mar 14, 2018, and over the history we have for it it has declined 79.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5130 per GM |
|---|---|
| All-time high | $2.4856 (Apr 11, 2018) |
| All-time low | $0.4696 (Nov 20, 2024) |
| 52-week high | $0.5637 |
| 52-week low | $0.5130 |
| Median price | $0.9423 |
| Average price | $0.9409 |
| Largest weekly change | +56.9% (Aug 21, 2019) |
| Weeks tracked | 434 |
| Tracking since | Mar 14, 2018 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 10% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Acella Pharmaceuticals, LLC manufacturer profile
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Drug market
Hydroquinone market comparison
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Therapeutic class
Melanin Synthesis Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROQUINONE 4% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for HYDROQUINONE 4% CREAM, manufactured by Acella Pharmaceuticals, LLC, is $0.5130 per GM (NDC 42192015101), effective Sep 30, 2026.
How has the price of HYDROQUINONE 4% CREAM changed over time?
Over the history we have for it, the NADAC for HYDROQUINONE 4% CREAM has declined 79.4%. It has been tracked across 434 weekly CMS publications since Mar 14, 2018.
What are the highest and lowest recorded NADAC prices for HYDROQUINONE 4% CREAM?
Since Mar 14, 2018, the NADAC for HYDROQUINONE 4% CREAM has ranged from a low of $0.4696 (Nov 20, 2024) to a high of $2.4856 (Apr 11, 2018), with a median of $0.9423 per GM.
Are there cheaper alternatives to HYDROQUINONE 4% CREAM?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROQUINONE 4% CREAM, is $0.4613 per GM — about 10% below HYDROQUINONE 4% CREAM.
Who manufactures HYDROQUINONE 4% CREAM?
HYDROQUINONE 4% CREAM (NDC 42192015101) is labeled by Acella Pharmaceuticals, LLC, and CMS classifies it as a generic product.