Product Information
HYDROQUINONE 4% CREAM is a generic product labeled by Nivagen Pharmaceuticals Inc., priced at $0.4539 per GM under NDC 75834013701. Its NADAC has been published 123 times since Apr 17, 2024.
The Low Outlier badge above means this manufacturer's average price in the Hydroquinone market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
40 mg/g
Manufacturer
Nivagen Pharmaceuticals Inc.NDC
75834013701
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
HYDROQUINONEApproval Type
Unapproved
On Market Since
8/17/2022
Pharmacological Classes
Price Statistics
The NADAC for HYDROQUINONE 4% CREAM has been published 123 times since Apr 17, 2024, and over the history we have for it it has declined 10.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4539 per GM |
|---|---|
| All-time high | $0.6562 (Jan 14, 2026) |
| All-time low | $0.4254 (Mar 19, 2025) |
| 52-week high | $0.6562 |
| 52-week low | $0.4445 |
| Median price | $0.4981 |
| Average price | $0.5113 |
| Largest weekly change | +31.9% (Jul 23, 2025) |
| Weeks tracked | 123 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROQUINONE 4% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for HYDROQUINONE 4% CREAM, manufactured by Nivagen Pharmaceuticals Inc., is $0.4539 per GM (NDC 75834013701), effective Aug 19, 2026.
How has the price of HYDROQUINONE 4% CREAM changed over time?
Over the history we have for it, the NADAC for HYDROQUINONE 4% CREAM has declined 10.4%. It has been tracked across 123 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for HYDROQUINONE 4% CREAM?
Since Apr 17, 2024, the NADAC for HYDROQUINONE 4% CREAM has ranged from a low of $0.4254 (Mar 19, 2025) to a high of $0.6562 (Jan 14, 2026), with a median of $0.4981 per GM.
Are there cheaper alternatives to HYDROQUINONE 4% CREAM?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROQUINONE 4% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROQUINONE 4% CREAM?
HYDROQUINONE 4% CREAM (NDC 75834013701) is labeled by Nivagen Pharmaceuticals Inc., and CMS classifies it as a generic product.