Product Information
METHYLPREDNISOLONE 400 MG/5 ML is a generic product labeled by Sagent Pharmaceuticals, priced at $13.0533 per ML under NDC 25021082105. Its NADAC has been published 87 times since Sep 18, 2024.
Strength
80 mg/mL
Manufacturer
Sagent PharmaceuticalsNDC
25021082105
Classification
Generic
Dosage Form
INJECTION, SUSPENSION
Route
INTRA-ARTICULAR; INTRALESIONAL; INTRAMUSCULAR; INTRASYNOVIAL; SOFT TISSUE
Last Updated
5/21/2025
Active Ingredients
METHYLPREDNISOLONE ACETATEApproval Type
Generic (ANDA)
FDA Application
ANDA201835On Market Since
11/15/2021
Pharmacological Classes
Price Statistics
The NADAC for METHYLPREDNISOLONE 400 MG/5 ML has been published 87 times since Sep 18, 2024, and over the history we have for it it has declined 12.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $13.0533 per ML |
|---|---|
| All-time high | $14.9732 (Oct 16, 2024) |
| All-time low | $13.0533 (May 21, 2025) |
| 52-week high | $13.0533 |
| 52-week low | $13.0533 |
| Median price | $13.0533 |
| Average price | $13.4333 |
| Largest weekly change | -5.1% (Oct 23, 2024) |
| Weeks tracked | 87 |
| Tracking since | Sep 18, 2024 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of METHYLPREDNISOLONE 400 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for METHYLPREDNISOLONE 400 MG/5 ML, manufactured by Sagent Pharmaceuticals, is $13.0533 per ML (NDC 25021082105), effective May 13, 2026.
How has the price of METHYLPREDNISOLONE 400 MG/5 ML changed over time?
Over the history we have for it, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has declined 12.8%. It has been tracked across 87 weekly CMS publications since Sep 18, 2024.
What are the highest and lowest recorded NADAC prices for METHYLPREDNISOLONE 400 MG/5 ML?
Since Sep 18, 2024, the NADAC for METHYLPREDNISOLONE 400 MG/5 ML has ranged from a low of $13.0533 (May 21, 2025) to a high of $14.9732 (Oct 16, 2024), with a median of $13.0533 per ML.
Are there cheaper alternatives to METHYLPREDNISOLONE 400 MG/5 ML?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, DEPO-MEDROL 400 MG/5 ML VIAL, is $10.8023 per ML — about 17% below METHYLPREDNISOLONE 400 MG/5 ML.
Who manufactures METHYLPREDNISOLONE 400 MG/5 ML?
METHYLPREDNISOLONE 400 MG/5 ML (NDC 25021082105) is labeled by Sagent Pharmaceuticals, and CMS classifies it as a generic product.
Related Drugs
Same classification