This NDC is on FDA's drug shortage list (posted Dec 15, 2021)

Product Information

DEPO-MEDROL 400 MG/5 ML VIAL is a brand product labeled by Pharmacia & Upjohn Company LLC, priced at $10.8023 per ML under NDC 00009030602. Its NADAC has been published 469 times since Nov 28, 2013.

FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DEPO-MEDROL 400 MG/5 ML VIAL

methylprednisolone acetate
$10.8023per ML

Strength

80 mg/mL

NDC

00009030602

Classification

Brand

Dosage Form

INJECTION, SUSPENSION

Route

INTRALESIONAL; INTRAMUSCULAR; INTRASYNOVIAL; SOFT TISSUE

Effective Date

4/23/2025

Active Ingredients

METHYLPREDNISOLONE ACETATE

Approval Type

New Drug (NDA)

FDA Application

NDA011757

FDA Approved

Before 1982

TE Code

AB

On Market Since

5/28/1959

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for DEPO-MEDROL 400 MG/5 ML VIAL has been published 469 times since Nov 28, 2013, and over the history we have for it it has risen 28.6%. The table below summarizes its recorded NADAC range and movement.

Current price$10.8023 per ML
All-time high$18.4101 (Jul 11, 2018)
All-time low$7.9275 (Jan 22, 2014)
52-week high$10.8023
52-week low$10.8023
Median price$12.6279
Average price$13.2157
Largest weekly change+23.7% (May 21, 2014)
Weeks tracked469
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

N/A

6M

0.0%

1Y

0.0%

3Y

-36.5%

5Y

-36.5%

All

+28.6%

Last surveyed Apr 15, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DEPO-MEDROL 400 MG/5 ML VIAL?

The current National Average Drug Acquisition Cost (NADAC) for DEPO-MEDROL 400 MG/5 ML VIAL, manufactured by Pharmacia & Upjohn Company LLC, is $10.8023 per ML (NDC 00009030602), effective Apr 15, 2026.

How has the price of DEPO-MEDROL 400 MG/5 ML VIAL changed over time?

Over the history we have for it, the NADAC for DEPO-MEDROL 400 MG/5 ML VIAL has risen 28.6%. It has been tracked across 469 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for DEPO-MEDROL 400 MG/5 ML VIAL?

Since Nov 28, 2013, the NADAC for DEPO-MEDROL 400 MG/5 ML VIAL has ranged from a low of $7.9275 (Jan 22, 2014) to a high of $18.4101 (Jul 11, 2018), with a median of $12.6279 per ML.

Are there cheaper alternatives to DEPO-MEDROL 400 MG/5 ML VIAL?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as DEPO-MEDROL 400 MG/5 ML VIAL in a comparable dosage form, but none are currently priced below it.

Who manufactures DEPO-MEDROL 400 MG/5 ML VIAL?

DEPO-MEDROL 400 MG/5 ML VIAL (NDC 00009030602) is labeled by Pharmacia & Upjohn Company LLC, and CMS classifies it as a brand product.

Is DEPO-MEDROL 400 MG/5 ML VIAL in shortage?

Yes — NDC 00009030602 is currently listed in FDA's drug shortage database (posted Dec 15, 2021).