Product Information

PROMETHAZINE-CODEINE SOLUTION is a generic product labeled by Cranbury Pharmaceuticals, LLC, priced at $0.0643 per ML under NDC 27808006502. Its NADAC has been published 407 times since Sep 12, 2018.

PROMETHAZINE-CODEINE SOLUTION

Promethazine Hydrochloride and Codeine Phosphate
$0.0643per ML
DEA Schedule CV

Strength

10; 6.25 mg/5mL; mg/5mL

NDC

27808006502

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA200386

On Market Since

3/12/2018

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist
Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE-CODEINE SOLUTION has been published 407 times since Sep 12, 2018, and over the history we have for it it has risen 245.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0643 per ML
All-time high$0.0655 (Mar 10, 2021)
All-time low$0.0186 (Sep 12, 2018)
52-week high$0.0643
52-week low$0.0399
Median price$0.0397
Average price$0.0390
Largest weekly change+39.3% (Sep 23, 2020)
Weeks tracked407
Tracking sinceSep 12, 2018

Price History

1W

0.0%

1M

+11.4%

3M

+27.4%

6M

+41.0%

1Y

+55.8%

3Y

+85.5%

5Y

+27.6%

All

+245.1%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE-CODEINE SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE-CODEINE SOLUTION, manufactured by Cranbury Pharmaceuticals, LLC, is $0.0643 per ML (NDC 27808006502), effective Jun 24, 2026.

How has the price of PROMETHAZINE-CODEINE SOLUTION changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE-CODEINE SOLUTION has risen 245.1%. It has been tracked across 407 weekly CMS publications since Sep 12, 2018.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE-CODEINE SOLUTION?

Since Sep 12, 2018, the NADAC for PROMETHAZINE-CODEINE SOLUTION has ranged from a low of $0.0186 (Sep 12, 2018) to a high of $0.0655 (Mar 10, 2021), with a median of $0.0397 per ML.

Are there cheaper alternatives to PROMETHAZINE-CODEINE SOLUTION?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as PROMETHAZINE-CODEINE SOLUTION, but none are currently priced below it.

Who manufactures PROMETHAZINE-CODEINE SOLUTION?

PROMETHAZINE-CODEINE SOLUTION (NDC 27808006502) is labeled by Cranbury Pharmaceuticals, LLC, and CMS classifies it as a generic product.