Product Information
PROMETHAZINE-CODEINE SOLUTION is a generic product labeled by Cranbury Pharmaceuticals, LLC, priced at $0.0697 per ML under NDC 27808006502. Its NADAC has been published 421 times since Sep 12, 2018.
FDA first approved this application on Jun 29, 2012. Its Orange Book therapeutic-equivalence code is AA.
Strength
10; 6.25 mg/5mL; mg/5mL
Manufacturer
Cranbury Pharmaceuticals, LLCNDC
27808006502
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CODEINE PHOSPHATE; PROMETHAZINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA200386FDA Approved
6/29/2012
TE Code
AA
On Market Since
3/12/2018
Pharmacological Classes
Price Statistics
The NADAC for PROMETHAZINE-CODEINE SOLUTION has been published 421 times since Sep 12, 2018, and over the history we have for it it has risen 274.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0697 per ML |
|---|---|
| All-time high | $0.0697 (Sep 30, 2026) |
| All-time low | $0.0186 (Sep 12, 2018) |
| 52-week high | $0.0697 |
| 52-week low | $0.0406 |
| Median price | $0.0397 |
| Average price | $0.0400 |
| Largest weekly change | +39.3% (Sep 23, 2020) |
| Weeks tracked | 421 |
| Tracking since | Sep 12, 2018 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Cranbury Pharmaceuticals, LLC manufacturer profile
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Drug market
Promethazine Hydrochloride and Codeine Phosphate market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of PROMETHAZINE-CODEINE SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE-CODEINE SOLUTION, manufactured by Cranbury Pharmaceuticals, LLC, is $0.0697 per ML (NDC 27808006502), effective Sep 30, 2026.
How has the price of PROMETHAZINE-CODEINE SOLUTION changed over time?
Over the history we have for it, the NADAC for PROMETHAZINE-CODEINE SOLUTION has risen 274.2%. It has been tracked across 421 weekly CMS publications since Sep 12, 2018.
What are the highest and lowest recorded NADAC prices for PROMETHAZINE-CODEINE SOLUTION?
Since Sep 12, 2018, the NADAC for PROMETHAZINE-CODEINE SOLUTION has ranged from a low of $0.0186 (Sep 12, 2018) to a high of $0.0697 (Sep 30, 2026), with a median of $0.0397 per ML.
Are there cheaper alternatives to PROMETHAZINE-CODEINE SOLUTION?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE-CODEINE SOLUTION in a comparable dosage form, but none are currently priced below it.
Who manufactures PROMETHAZINE-CODEINE SOLUTION?
PROMETHAZINE-CODEINE SOLUTION (NDC 27808006502) is labeled by Cranbury Pharmaceuticals, LLC, and CMS classifies it as a generic product.