Product Information

PROMETHAZINE-CODEINE SOLUTION is a generic product labeled by Quagen Pharmaceuticals LLC, priced at $0.0682 per ML under NDC 70752013912. Its NADAC has been published 283 times since Mar 24, 2021.

FDA first approved this application on Oct 8, 2020. Its Orange Book therapeutic-equivalence code is AA.

PROMETHAZINE-CODEINE SOLUTION

Promethazine Hydrochloride and Codeine Phosphate
$0.0682per ML
DEA Schedule CV

Strength

10; 6.25 mg/5mL; mg/5mL

NDC

70752013912

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA214238

FDA Approved

10/8/2020

TE Code

AA

On Market Since

10/8/2020

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist
Phenothiazine
Phenothiazines

Price Statistics

The NADAC for PROMETHAZINE-CODEINE SOLUTION has been published 283 times since Mar 24, 2021, and over the history we have for it it has risen 27.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0682 per ML
All-time high$0.0682 (Aug 19, 2026)
All-time low$0.0301 (Feb 22, 2023)
52-week high$0.0682
52-week low$0.0399
Median price$0.0411
Average price$0.0436
Largest weekly change+28.2% (May 19, 2021)
Weeks tracked283
Tracking sinceMar 24, 2021

Price History

1W

+2.3%

1M

+2.3%

3M

+18.3%

6M

+36.2%

1Y

+71.1%

3Y

+90.0%

5Y

+35.2%

All

+27.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of PROMETHAZINE-CODEINE SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for PROMETHAZINE-CODEINE SOLUTION, manufactured by Quagen Pharmaceuticals LLC, is $0.0682 per ML (NDC 70752013912), effective Aug 19, 2026.

How has the price of PROMETHAZINE-CODEINE SOLUTION changed over time?

Over the history we have for it, the NADAC for PROMETHAZINE-CODEINE SOLUTION has risen 27.6%. It has been tracked across 283 weekly CMS publications since Mar 24, 2021.

What are the highest and lowest recorded NADAC prices for PROMETHAZINE-CODEINE SOLUTION?

Since Mar 24, 2021, the NADAC for PROMETHAZINE-CODEINE SOLUTION has ranged from a low of $0.0301 (Feb 22, 2023) to a high of $0.0682 (Aug 19, 2026), with a median of $0.0411 per ML.

Are there cheaper alternatives to PROMETHAZINE-CODEINE SOLUTION?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as PROMETHAZINE-CODEINE SOLUTION in a comparable dosage form, but none are currently priced below it.

Who manufactures PROMETHAZINE-CODEINE SOLUTION?

PROMETHAZINE-CODEINE SOLUTION (NDC 70752013912) is labeled by Quagen Pharmaceuticals LLC, and CMS classifies it as a generic product.