Product Information
HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET is a generic product labeled by Cranbury Pharmaceuticals, LLC, priced at $0.1754 per EA under NDC 27808011401. Its NADAC has been published 529 times since Aug 17, 2016.
FDA first approved this application on Mar 27, 2013. Its Orange Book therapeutic-equivalence code is AA.
Strength
300; 5 mg/1; mg/1
Manufacturer
Cranbury Pharmaceuticals, LLCNDC
27808011401
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; HYDROCODONE BITARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA202214FDA Approved
3/27/2013
TE Code
AA
On Market Since
4/7/2016
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has been published 529 times since Aug 17, 2016, and over the history we have for it it has declined 84.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1754 per EA |
|---|---|
| All-time high | $1.1464 (Oct 12, 2016) |
| All-time low | $0.1228 (Dec 22, 2021) |
| 52-week high | $0.1754 |
| 52-week low | $0.1496 |
| Median price | $0.2178 |
| Average price | $0.3852 |
| Largest weekly change | +77.7% (Sep 23, 2020) |
| Weeks tracked | 529 |
| Tracking since | Aug 17, 2016 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 15% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Cranbury Pharmaceuticals, LLC manufacturer profile
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Drug market
Hydrocodone Bitartrate and Acetaminophen market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET, manufactured by Cranbury Pharmaceuticals, LLC, is $0.1754 per EA (NDC 27808011401), effective Sep 30, 2026.
How has the price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has declined 84.6%. It has been tracked across 529 weekly CMS publications since Aug 17, 2016.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
Since Aug 17, 2016, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has ranged from a low of $0.1228 (Dec 22, 2021) to a high of $1.1464 (Oct 12, 2016), with a median of $0.2178 per EA.
Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET, is $0.1496 per EA — about 15% below HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET.
Who manufactures HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?
HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET (NDC 27808011401) is labeled by Cranbury Pharmaceuticals, LLC, and CMS classifies it as a generic product.