Product Information

HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET is a generic product labeled by Cranbury Pharmaceuticals, LLC, priced at $0.1654 per EA under NDC 27808011401. Its NADAC has been published 523 times since Aug 17, 2016.

FDA first approved this application on Mar 27, 2013. Its Orange Book therapeutic-equivalence code is AA.

HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET

Hydrocodone Bitartrate and Acetaminophen
$0.1654per EA
DEA Schedule CII

Strength

300; 5 mg/1; mg/1

NDC

27808011401

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA202214

FDA Approved

3/27/2013

TE Code

AA

On Market Since

4/7/2016

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has been published 523 times since Aug 17, 2016, and over the history we have for it it has declined 85.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1654 per EA
All-time high$1.1464 (Oct 12, 2016)
All-time low$0.1228 (Dec 22, 2021)
52-week high$0.1756
52-week low$0.1496
Median price$0.2178
Average price$0.3877
Largest weekly change+77.7% (Sep 23, 2020)
Weeks tracked523
Tracking sinceAug 17, 2016

Price History

1W

+5.8%

1M

+5.8%

3M

+2.3%

6M

+10.5%

1Y

-5.9%

3Y

-1.7%

5Y

-48.1%

All

-85.5%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 10% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET, manufactured by Cranbury Pharmaceuticals, LLC, is $0.1654 per EA (NDC 27808011401), effective Aug 19, 2026.

How has the price of HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET changed over time?

Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has declined 85.5%. It has been tracked across 523 weekly CMS publications since Aug 17, 2016.

What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

Since Aug 17, 2016, the NADAC for HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET has ranged from a low of $0.1228 (Dec 22, 2021) to a high of $1.1464 (Oct 12, 2016), with a median of $0.2178 per EA.

Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET, is $0.1496 per EA — about 10% below HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET.

Who manufactures HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET?

HYDROCODONE-ACETAMINOPHEN 5-300 MG TABLET (NDC 27808011401) is labeled by Cranbury Pharmaceuticals, LLC, and CMS classifies it as a generic product.