Product Information

HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET is a generic product labeled by Cranbury Pharmaceuticals, LLC, priced at $0.2411 per EA under NDC 27808011602. Its NADAC has been published 484 times since Aug 17, 2016.

FDA first approved this application on Mar 27, 2013. Its Orange Book therapeutic-equivalence code is AA.

HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET

Hydrocodone Bitartrate and Acetaminophen
$0.2411per EA
DEA Schedule CII

Strength

300; 10 mg/1; mg/1

NDC

27808011602

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

11/19/2025

Approval Type

Generic (ANDA)

FDA Application

ANDA202214

FDA Approved

3/27/2013

TE Code

AA

On Market Since

4/7/2016

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET has been published 484 times since Aug 17, 2016, and over the history we have for it it has declined 85.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2411 per EA
All-time high$1.6767 (Mar 15, 2017)
All-time low$0.1638 (May 17, 2023)
52-week high$0.2493
52-week low$0.2411
Median price$0.3895
Average price$0.6391
Largest weekly change+116.2% (Aug 19, 2020)
Weeks tracked484
Tracking sinceAug 17, 2016

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-3.3%

3Y

-12.9%

5Y

-42.8%

All

-85.6%

Last surveyed Nov 19, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET, manufactured by Cranbury Pharmaceuticals, LLC, is $0.2411 per EA (NDC 27808011602), effective Nov 19, 2025.

How has the price of HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET changed over time?

Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET has declined 85.6%. It has been tracked across 484 weekly CMS publications since Aug 17, 2016.

What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?

Since Aug 17, 2016, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET has ranged from a low of $0.1638 (May 17, 2023) to a high of $1.6767 (Mar 15, 2017), with a median of $0.3895 per EA.

Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET, is $0.2347 per EA — about 3% below HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET.

Who manufactures HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?

HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET (NDC 27808011602) is labeled by Cranbury Pharmaceuticals, LLC, and CMS classifies it as a generic product.