Product Information
HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.2347 per EA under NDC 43386035305. Its NADAC has been published 477 times since May 10, 2017.
FDA first approved this application on Nov 14, 2016.
Strength
300; 10 mg/1; mg/1
Manufacturer
Lupin Pharmaceuticals Inc.NDC
43386035305
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
6/17/2026
Active Ingredients
ACETAMINOPHEN; HYDROCODONE BITARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA206142FDA Approved
11/14/2016
On Market Since
11/14/2016
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET has been published 477 times since May 10, 2017, and over the history we have for it it has declined 84.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2347 per EA |
|---|---|
| All-time high | $1.5892 (Aug 16, 2017) |
| All-time low | $0.1638 (May 17, 2023) |
| 52-week high | $0.2493 |
| 52-week low | $0.2347 |
| Median price | $0.3482 |
| Average price | $0.5358 |
| Largest weekly change | +116.2% (Aug 19, 2020) |
| Weeks tracked | 477 |
| Tracking since | May 10, 2017 |
1W
N/A
1M
N/A
3M
-1.2%
6M
-2.2%
1Y
-5.8%
3Y
-15.2%
5Y
-44.3%
All
-84.5%
Last surveyed Jun 24, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET, manufactured by Lupin Pharmaceuticals Inc., is $0.2347 per EA (NDC 43386035305), effective Jun 24, 2026.
How has the price of HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET has declined 84.5%. It has been tracked across 477 weekly CMS publications since May 10, 2017.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?
Since May 10, 2017, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET has ranged from a low of $0.1638 (May 17, 2023) to a high of $1.5892 (Aug 16, 2017), with a median of $0.3482 per EA.
Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET?
HYDROCODONE-ACETAMINOPHEN 10-300 MG TABLET (NDC 43386035305) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.