Product Information

AMITRIPTYLINE HCL 100 MG TAB is a generic product labeled by Unichem Pharmaceuticals (USA) Inc., priced at $0.1455 per EA under NDC 29300042301. Its NADAC has been published 266 times since Jul 21, 2021.

FDA first approved this application on May 19, 2021. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

AMITRIPTYLINE HCL 100 MG TAB

Amitriptyline Hydrochloride
$0.1455per EA

Strength

100 mg/1

NDC

29300042301

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

AMITRIPTYLINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA214548

FDA Approved

5/19/2021

TE Code

AB

On Market Since

5/26/2021

Pharmacological Classes

Price Statistics

The NADAC for AMITRIPTYLINE HCL 100 MG TAB has been published 266 times since Jul 21, 2021, and over the history we have for it it has declined 58.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1455 per EA
All-time high$0.3643 (Sep 15, 2021)
All-time low$0.1180 (Nov 20, 2024)
52-week high$0.1773
52-week low$0.1455
Median price$0.1679
Average price$0.1906
Largest weekly change-35.1% (Jun 22, 2022)
Weeks tracked266
Tracking sinceJul 21, 2021

Price History

1W

-0.2%

1M

-0.2%

3M

-9.1%

6M

-14.4%

1Y

-14.6%

3Y

-28.2%

5Y

-60.1%

All

-58.6%

Generic Alternatives

The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of AMITRIPTYLINE HCL 100 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for AMITRIPTYLINE HCL 100 MG TAB, manufactured by Unichem Pharmaceuticals (USA) Inc., is $0.1455 per EA (NDC 29300042301), effective Aug 19, 2026.

How has the price of AMITRIPTYLINE HCL 100 MG TAB changed over time?

Over the history we have for it, the NADAC for AMITRIPTYLINE HCL 100 MG TAB has declined 58.6%. It has been tracked across 266 weekly CMS publications since Jul 21, 2021.

What are the highest and lowest recorded NADAC prices for AMITRIPTYLINE HCL 100 MG TAB?

Since Jul 21, 2021, the NADAC for AMITRIPTYLINE HCL 100 MG TAB has ranged from a low of $0.1180 (Nov 20, 2024) to a high of $0.3643 (Sep 15, 2021), with a median of $0.1679 per EA.

Are there cheaper alternatives to AMITRIPTYLINE HCL 100 MG TAB?

9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as AMITRIPTYLINE HCL 100 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures AMITRIPTYLINE HCL 100 MG TAB?

AMITRIPTYLINE HCL 100 MG TAB (NDC 29300042301) is labeled by Unichem Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.