Product Information
AMITRIPTYLINE HCL 100 MG TAB is a generic product labeled by Advagen Pharma Ltd., priced at $0.1427 per EA under NDC 72888007101. Its NADAC has been published 82 times since Mar 12, 2025.
FDA first approved this application on May 1, 2023. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
100 mg/1
Manufacturer
Advagen Pharma Ltd.NDC
72888007101
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
AMITRIPTYLINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA215376FDA Approved
5/1/2023
TE Code
AB
On Market Since
5/1/2023
Pharmacological Classes
Price Statistics
The NADAC for AMITRIPTYLINE HCL 100 MG TAB has been published 82 times since Mar 12, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1427 per EA |
|---|---|
| All-time high | $0.1773 (Nov 12, 2025) |
| All-time low | $0.1405 (Mar 12, 2025) |
| 52-week high | $0.1773 |
| 52-week low | $0.1427 |
| Median price | $0.1672 |
| Average price | $0.1619 |
| Largest weekly change | +8.2% (Mar 19, 2025) |
| Weeks tracked | 82 |
| Tracking since | Mar 12, 2025 |
Generic Alternatives
The matcher finds 9 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Advagen Pharma Ltd. manufacturer profile
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Drug market
Amitriptyline Hydrochloride market comparison
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Therapeutic class
Tricyclic Antidepressant class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of AMITRIPTYLINE HCL 100 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for AMITRIPTYLINE HCL 100 MG TAB, manufactured by Advagen Pharma Ltd., is $0.1427 per EA (NDC 72888007101), effective Sep 30, 2026.
How has the price of AMITRIPTYLINE HCL 100 MG TAB changed over time?
Over the history we have for it, the NADAC for AMITRIPTYLINE HCL 100 MG TAB has held within roughly two percent of its current level. It has been tracked across 82 weekly CMS publications since Mar 12, 2025.
What are the highest and lowest recorded NADAC prices for AMITRIPTYLINE HCL 100 MG TAB?
Since Mar 12, 2025, the NADAC for AMITRIPTYLINE HCL 100 MG TAB has ranged from a low of $0.1405 (Mar 12, 2025) to a high of $0.1773 (Nov 12, 2025), with a median of $0.1672 per EA.
Are there cheaper alternatives to AMITRIPTYLINE HCL 100 MG TAB?
9 manufacturers publish a NADAC-priced product with the same active ingredient and strength as AMITRIPTYLINE HCL 100 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures AMITRIPTYLINE HCL 100 MG TAB?
AMITRIPTYLINE HCL 100 MG TAB (NDC 72888007101) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.