Product Information

DONEPEZIL HCL 5 MG TABLET is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.0450 per EA under NDC 33342002744. Its NADAC has been published 492 times since Jun 18, 2014.

FDA first approved this application on Aug 17, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

DONEPEZIL HCL 5 MG TABLET

Donepezil Hydrochloride
$0.0450per EA

Strength

5 mg/1

NDC

33342002744

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

4/23/2025

Active Ingredients

DONEPEZIL HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA201146

FDA Approved

8/17/2012

TE Code

AB

On Market Since

8/17/2012

Pharmacological Classes

Cholinesterase Inhibitor
Cholinesterase Inhibitors

Price Statistics

The NADAC for DONEPEZIL HCL 5 MG TABLET has been published 492 times since Jun 18, 2014, and over the history we have for it it has declined 39.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0450 per EA
All-time high$0.0872 (Aug 13, 2014)
All-time low$0.0334 (May 22, 2024)
Median price$0.0527
Average price$0.0529
Largest weekly change+28.3% (Nov 22, 2023)
Weeks tracked492
Tracking sinceJun 18, 2014

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

N/A

3Y

+7.4%

5Y

-21.3%

All

-39.9%

Last surveyed May 14, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of DONEPEZIL HCL 5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for DONEPEZIL HCL 5 MG TABLET, manufactured by Macleods Pharmaceuticals Limited, is $0.0450 per EA (NDC 33342002744), effective May 14, 2025.

How has the price of DONEPEZIL HCL 5 MG TABLET changed over time?

Over the history we have for it, the NADAC for DONEPEZIL HCL 5 MG TABLET has declined 39.9%. It has been tracked across 492 weekly CMS publications since Jun 18, 2014.

What are the highest and lowest recorded NADAC prices for DONEPEZIL HCL 5 MG TABLET?

Since Jun 18, 2014, the NADAC for DONEPEZIL HCL 5 MG TABLET has ranged from a low of $0.0334 (May 22, 2024) to a high of $0.0872 (Aug 13, 2014), with a median of $0.0527 per EA.

Are there cheaper alternatives to DONEPEZIL HCL 5 MG TABLET?

Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DONEPEZIL HCL 5 MG TABLET, is $0.0435 per EA — about 3% below DONEPEZIL HCL 5 MG TABLET.

Who manufactures DONEPEZIL HCL 5 MG TABLET?

DONEPEZIL HCL 5 MG TABLET (NDC 33342002744) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.