Product Information
DONEPEZIL HCL ODT 5 MG TABLET is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.2807 per EA under NDC 33342002907. Its NADAC has been published 660 times since Jan 15, 2014.
FDA first approved this application on Dec 14, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Macleods Pharmaceuticals LimitedNDC
33342002907
Classification
Generic
Dosage Form
TABLET, ORALLY DISINTEGRATING
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DONEPEZIL HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA201787FDA Approved
12/14/2012
TE Code
AB
On Market Since
12/14/2012
Pharmacological Classes
Price Statistics
The NADAC for DONEPEZIL HCL ODT 5 MG TABLET has been published 660 times since Jan 15, 2014, and over the history we have for it it has declined 23.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2807 per EA |
|---|---|
| All-time high | $0.6636 (Feb 12, 2014) |
| All-time low | $0.1610 (Jul 20, 2016) |
| 52-week high | $0.2917 |
| 52-week low | $0.2623 |
| Median price | $0.2516 |
| Average price | $0.2504 |
| Largest weekly change | +84.1% (Nov 19, 2014) |
| Weeks tracked | 660 |
| Tracking since | Jan 15, 2014 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 84% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Macleods Pharmaceuticals Limited manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Donepezil Hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Cholinesterase Inhibitor class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DONEPEZIL HCL ODT 5 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for DONEPEZIL HCL ODT 5 MG TABLET, manufactured by Macleods Pharmaceuticals Limited, is $0.2807 per EA (NDC 33342002907), effective Sep 30, 2026.
How has the price of DONEPEZIL HCL ODT 5 MG TABLET changed over time?
Over the history we have for it, the NADAC for DONEPEZIL HCL ODT 5 MG TABLET has declined 23.8%. It has been tracked across 660 weekly CMS publications since Jan 15, 2014.
What are the highest and lowest recorded NADAC prices for DONEPEZIL HCL ODT 5 MG TABLET?
Since Jan 15, 2014, the NADAC for DONEPEZIL HCL ODT 5 MG TABLET has ranged from a low of $0.1610 (Jul 20, 2016) to a high of $0.6636 (Feb 12, 2014), with a median of $0.2516 per EA.
Are there cheaper alternatives to DONEPEZIL HCL ODT 5 MG TABLET?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DONEPEZIL HCL 5 MG TABLET, is $0.0440 per EA — about 84% below DONEPEZIL HCL ODT 5 MG TABLET.
Who manufactures DONEPEZIL HCL ODT 5 MG TABLET?
DONEPEZIL HCL ODT 5 MG TABLET (NDC 33342002907) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.