Product Information

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.0573 per EA under NDC 33342005010. Its NADAC has been published 580 times since Jul 15, 2015.

FDA first approved this application on Aug 9, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB

Losartan potassium and Hydrochlorothiazide
$0.0573per EA

Strength

12.5; 50 mg/1; mg/1

NDC

33342005010

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA202289

FDA Approved

8/9/2012

TE Code

AB

On Market Since

9/10/2012

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has been published 580 times since Jul 15, 2015, and over the history we have for it it has declined 31.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0573 per EA
All-time high$0.1854 (Apr 15, 2020)
All-time low$0.0573 (Aug 19, 2026)
52-week high$0.0797
52-week low$0.0573
Median price$0.0824
Average price$0.1009
Largest weekly change+46.8% (Dec 18, 2019)
Weeks tracked580
Tracking sinceJul 15, 2015

Price History

1W

-4.7%

1M

-4.7%

3M

-7.3%

6M

-18.7%

1Y

-28.1%

3Y

-44.0%

5Y

-62.3%

All

-31.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, manufactured by Macleods Pharmaceuticals Limited, is $0.0573 per EA (NDC 33342005010), effective Aug 19, 2026.

How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB changed over time?

Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has declined 31.6%. It has been tracked across 580 weekly CMS publications since Jul 15, 2015.

What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

Since Jul 15, 2015, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has ranged from a low of $0.0573 (Aug 19, 2026) to a high of $0.1854 (Apr 15, 2020), with a median of $0.0824 per EA.

Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB in a comparable dosage form, but none are currently priced below it.

Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?

LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB (NDC 33342005010) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.