Product Information
LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.0573 per EA under NDC 33342005044. Its NADAC has been published 256 times since Sep 29, 2021.
FDA first approved this application on Aug 9, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
12.5; 50 mg/1; mg/1
Manufacturer
Macleods Pharmaceuticals LimitedNDC
33342005044
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUMApproval Type
Generic (ANDA)
FDA Application
ANDA202289FDA Approved
8/9/2012
TE Code
AB
On Market Since
9/10/2012
Pharmacological Classes
Price Statistics
The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has been published 256 times since Sep 29, 2021, and over the history we have for it it has declined 61.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0573 per EA |
|---|---|
| All-time high | $0.1848 (Apr 13, 2022) |
| All-time low | $0.0573 (Aug 19, 2026) |
| 52-week high | $0.0797 |
| 52-week low | $0.0573 |
| Median price | $0.0923 |
| Average price | $0.1013 |
| Largest weekly change | -22.4% (Nov 20, 2024) |
| Weeks tracked | 256 |
| Tracking since | Sep 29, 2021 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB, manufactured by Macleods Pharmaceuticals Limited, is $0.0573 per EA (NDC 33342005044), effective Aug 19, 2026.
How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB changed over time?
Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has declined 61.8%. It has been tracked across 256 weekly CMS publications since Sep 29, 2021.
What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
Since Sep 29, 2021, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB has ranged from a low of $0.0573 (Aug 19, 2026) to a high of $0.1848 (Apr 13, 2022), with a median of $0.0923 per EA.
Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB?
LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB (NDC 33342005044) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.