Product Information
LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB is a generic product labeled by Macleods Pharmaceuticals Limited, priced at $0.0793 per EA under NDC 33342005210. Its NADAC has been published 586 times since Jul 15, 2015.
FDA first approved this application on Aug 9, 2012. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25; 100 mg/1; mg/1
Manufacturer
Macleods Pharmaceuticals LimitedNDC
33342005210
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
HYDROCHLOROTHIAZIDE; LOSARTAN POTASSIUMApproval Type
Generic (ANDA)
FDA Application
ANDA202289FDA Approved
8/9/2012
TE Code
AB
On Market Since
5/3/2012
Pharmacological Classes
Price Statistics
The NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB has been published 586 times since Jul 15, 2015, and over the history we have for it it has declined 30.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0793 per EA |
|---|---|
| All-time high | $0.2811 (May 11, 2022) |
| All-time low | $0.0771 (Jan 23, 2019) |
| 52-week high | $0.0876 |
| 52-week low | $0.0771 |
| Median price | $0.1051 |
| Average price | $0.1212 |
| Largest weekly change | +41.4% (Jan 29, 2020) |
| Weeks tracked | 586 |
| Tracking since | Jul 15, 2015 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Macleods Pharmaceuticals Limited manufacturer profile
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Drug market
Losartan potassium and Hydrochlorothiazide market comparison
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Therapeutic class
Angiotensin 2 Receptor Blocker class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB, manufactured by Macleods Pharmaceuticals Limited, is $0.0793 per EA (NDC 33342005210), effective Sep 30, 2026.
How has the price of LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB changed over time?
Over the history we have for it, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB has declined 30.9%. It has been tracked across 586 weekly CMS publications since Jul 15, 2015.
What are the highest and lowest recorded NADAC prices for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?
Since Jul 15, 2015, the NADAC for LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB has ranged from a low of $0.0771 (Jan 23, 2019) to a high of $0.2811 (May 11, 2022), with a median of $0.1051 per EA.
Are there cheaper alternatives to LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB?
LOSARTAN-HYDROCHLOROTHIAZIDE 100-25 MG TAB (NDC 33342005210) is labeled by Macleods Pharmaceuticals Limited, and CMS classifies it as a generic product.