Product Information
BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB is a generic product labeled by Burel Pharmaceuticals, LLC, priced at $0.8746 per EA under NDC 35573045502. Its NADAC has been published 129 times since Apr 17, 2024.
FDA first approved this application on Apr 7, 2022. Its Orange Book therapeutic-equivalence code is AA.
Strength
300; 50 mg/1; mg/1
Manufacturer
Burel Pharmaceuticals, LLCNDC
35573045502
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ACETAMINOPHEN; BUTALBITALApproval Type
Generic (ANDA)
FDA Application
ANDA214088FDA Approved
4/7/2022
TE Code
AA
On Market Since
12/1/2022
Pharmacological Classes
Price Statistics
The NADAC for BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB has been published 129 times since Apr 17, 2024, and over the history we have for it it has declined 66.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.8746 per EA |
|---|---|
| All-time high | $3.5911 (Dec 11, 2024) |
| All-time low | $0.8746 (Sep 23, 2026) |
| 52-week high | $1.5794 |
| 52-week low | $0.8746 |
| Median price | $1.8264 |
| Average price | $2.1522 |
| Largest weekly change | -42.9% (Sep 23, 2026) |
| Weeks tracked | 129 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the butalbital and acetaminophen market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Burel Pharmaceuticals, LLC manufacturer profile
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Drug market
butalbital and acetaminophen market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Barbiturate class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB, manufactured by Burel Pharmaceuticals, LLC, is $0.8746 per EA (NDC 35573045502), effective Sep 30, 2026.
How has the price of BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB changed over time?
Over the history we have for it, the NADAC for BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB has declined 66.6%. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB?
Since Apr 17, 2024, the NADAC for BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB has ranged from a low of $0.8746 (Sep 23, 2026) to a high of $3.5911 (Dec 11, 2024), with a median of $1.8264 per EA.
Are there cheaper alternatives to BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB?
No other NADAC-published product currently shares the active ingredient and strength of BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB?
BUTALBITAL-ACETAMINOPHEN 50-300 MG TAB (NDC 35573045502) is labeled by Burel Pharmaceuticals, LLC, and CMS classifies it as a generic product.