Product Information
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET is a generic product labeled by Actavis Pharma, Inc., priced at $0.1233 per EA under NDC 00591336905. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Nov 9, 1984. Its Orange Book therapeutic-equivalence code is AA.
The High Outlier badge above means this manufacturer's average price in the Butalbital, Acetaminophen, and Caffeine market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET
Butalbital, Acetaminophen, and CaffeineStrength
325; 50; 40 mg/1; mg/1; mg/1
Manufacturer
Actavis Pharma, Inc.NDC
00591336905
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; BUTALBITAL; CAFFEINEApproval Type
Generic (ANDA)
FDA Application
ANDA088616FDA Approved
11/9/1984
TE Code
AA
On Market Since
12/13/2007
Pharmacological Classes
Price Statistics
The NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 49.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1233 per EA |
|---|---|
| All-time high | $0.8719 (May 11, 2016) |
| All-time low | $0.0825 (Nov 28, 2013) |
| 52-week high | $0.1447 |
| 52-week low | $0.1218 |
| Median price | $0.1951 |
| Average price | $0.3122 |
| Largest weekly change | +538.4% (Jun 18, 2014) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET, manufactured by Actavis Pharma, Inc., is $0.1233 per EA (NDC 00591336905), effective Aug 19, 2026.
How has the price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has risen 49.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
Since Nov 28, 2013, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has ranged from a low of $0.0825 (Nov 28, 2013) to a high of $0.8719 (May 11, 2016), with a median of $0.1951 per EA.
Are there cheaper alternatives to BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET (NDC 00591336905) is labeled by Actavis Pharma, Inc., and CMS classifies it as a generic product.