Product Information
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET is a generic product labeled by Major Pharmaceuticals, priced at $0.1233 per EA under NDC 00904693806. Its NADAC has been published 340 times since Feb 19, 2020.
FDA first approved this application on Sep 13, 2012. Its Orange Book therapeutic-equivalence code is AA.
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET
Butalbital, Acetaminophen, and CaffeineStrength
325; 50; 40 mg/1; mg/1; mg/1
Manufacturer
Major PharmaceuticalsNDC
00904693806
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; BUTALBITAL; CAFFEINEApproval Type
Generic (ANDA)
FDA Application
ANDA200243FDA Approved
9/13/2012
TE Code
AA
On Market Since
9/13/2012
Pharmacological Classes
Price Statistics
The NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has been published 340 times since Feb 19, 2020, and over the history we have for it it has declined 47.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1233 per EA |
|---|---|
| All-time high | $0.2484 (Apr 15, 2020) |
| All-time low | $0.1112 (Nov 20, 2024) |
| 52-week high | $0.1447 |
| 52-week low | $0.1218 |
| Median price | $0.1597 |
| Average price | $0.1639 |
| Largest weekly change | +35.2% (Aug 21, 2024) |
| Weeks tracked | 340 |
| Tracking since | Feb 19, 2020 |
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET, manufactured by Major Pharmaceuticals, is $0.1233 per EA (NDC 00904693806), effective Aug 19, 2026.
How has the price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has declined 47.5%. It has been tracked across 340 weekly CMS publications since Feb 19, 2020.
What are the highest and lowest recorded NADAC prices for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
Since Feb 19, 2020, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has ranged from a low of $0.1112 (Nov 20, 2024) to a high of $0.2484 (Apr 15, 2020), with a median of $0.1597 per EA.
Are there cheaper alternatives to BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?
BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET (NDC 00904693806) is labeled by Major Pharmaceuticals, and CMS classifies it as a generic product.