Product Information

BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET is a generic product labeled by AvPAK, priced at $0.1218 per EA under NDC 50268055313. Its NADAC has been published 172 times since Mar 15, 2023.

BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET

Butalbital, Acetaminophen, and Caffeine
$0.1218per EA
DEA Schedule CIII

Strength

325; 50; 40 mg/1; mg/1; mg/1

Manufacturer

AvPAK

NDC

50268055313

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA209587

On Market Since

8/11/2022

Pharmacological Classes

Barbiturate
Barbiturates
Central Nervous System Stimulant
Central Nervous System Stimulation
Methylxanthine
Xanthines

Price Statistics

The NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has been published 172 times since Mar 15, 2023, and over the history we have for it it has declined 17.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1218 per EA
All-time high$0.1664 (Oct 16, 2024)
All-time low$0.1112 (Nov 20, 2024)
52-week high$0.1493
52-week low$0.1218
Median price$0.1476
Average price$0.1442
Largest weekly change+35.2% (Aug 21, 2024)
Weeks tracked172
Tracking sinceMar 15, 2023

Price History

1W

0.0%

1M

-0.8%

3M

-7.0%

6M

-12.3%

1Y

-18.4%

3Y

-23.6%

5Y

N/A

All

-17.6%

Generic Alternatives

The matcher finds 6 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 6 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET, manufactured by AvPAK, is $0.1218 per EA (NDC 50268055313), effective Jun 24, 2026.

How has the price of BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has declined 17.6%. It has been tracked across 172 weekly CMS publications since Mar 15, 2023.

What are the highest and lowest recorded NADAC prices for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?

Since Mar 15, 2023, the NADAC for BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET has ranged from a low of $0.1112 (Nov 20, 2024) to a high of $0.1664 (Oct 16, 2024), with a median of $0.1476 per EA.

Are there cheaper alternatives to BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?

6 NADAC-published products share the same active ingredient, strength, and dosage form as BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET, but none are currently priced below it.

Who manufactures BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET?

BUTALBITAL-ACETAMINOPHEN-CAFFEINE 50-325-40 MG TABLET (NDC 50268055313) is labeled by AvPAK, and CMS classifies it as a generic product.