Product Information
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB is a generic product labeled by Edenbridge Pharmaceuticals LLC, priced at $0.2133 per EA under NDC 42799092001. Its NADAC has been published 308 times since Nov 11, 2020.
FDA first approved this application on Jul 9, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB
Bisoprolol Fumarate and HydrochlorothiazideStrength
2.5; 6.25 mg/1; mg/1
Manufacturer
Edenbridge Pharmaceuticals LLCNDC
42799092001
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BISOPROLOL FUMARATE; HYDROCHLOROTHIAZIDEApproval Type
Generic (ANDA)
FDA Application
ANDA212678FDA Approved
7/9/2020
TE Code
AB
On Market Since
4/30/2019
Pharmacological Classes
Price Statistics
The NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has been published 308 times since Nov 11, 2020, and over the history we have for it it has declined 50.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2133 per EA |
|---|---|
| All-time high | $0.4591 (Dec 16, 2020) |
| All-time low | $0.1729 (Nov 20, 2024) |
| 52-week high | $0.2146 |
| 52-week low | $0.1855 |
| Median price | $0.2580 |
| Average price | $0.2758 |
| Largest weekly change | +63.0% (Nov 22, 2023) |
| Weeks tracked | 308 |
| Tracking since | Nov 11, 2020 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Edenbridge Pharmaceuticals LLC manufacturer profile
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Drug market
Bisoprolol Fumarate and Hydrochlorothiazide market comparison
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Therapeutic class
Thiazide Diuretic class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
The current National Average Drug Acquisition Cost (NADAC) for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB, manufactured by Edenbridge Pharmaceuticals LLC, is $0.2133 per EA (NDC 42799092001), effective Sep 30, 2026.
How has the price of BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB changed over time?
Over the history we have for it, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has declined 50.9%. It has been tracked across 308 weekly CMS publications since Nov 11, 2020.
What are the highest and lowest recorded NADAC prices for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
Since Nov 11, 2020, the NADAC for BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB has ranged from a low of $0.1729 (Nov 20, 2024) to a high of $0.4591 (Dec 16, 2020), with a median of $0.2580 per EA.
Are there cheaper alternatives to BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB in a comparable dosage form, but none are currently priced below it.
Who manufactures BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB?
BISOPROLOL-HYDROCHLOROTHIAZIDE 2.5-6.25 MG TB (NDC 42799092001) is labeled by Edenbridge Pharmaceuticals LLC, and CMS classifies it as a generic product.