Product Information

CLOBETASOL 0.05% SOLUTION is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.1204 per ML under NDC 43386002860. Its NADAC has been published 465 times since Mar 29, 2017.

FDA first approved this application on Nov 23, 2015. Its Orange Book therapeutic-equivalence code is AT.

CLOBETASOL 0.05% SOLUTION

clobetasol propionate
$0.1204per ML

Strength

.5 mg/mL

NDC

43386002860

Classification

Generic

Dosage Form

SOLUTION

Route

TOPICAL

Effective Date

2/18/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA206075

FDA Approved

11/23/2015

TE Code

AT

On Market Since

11/23/2015

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% SOLUTION has been published 465 times since Mar 29, 2017, and over the history we have for it it has declined 92.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1204 per ML
All-time high$1.5999 (Apr 12, 2017)
All-time low$0.1204 (Feb 18, 2026)
52-week high$0.1917
52-week low$0.1204
Median price$0.4607
Average price$0.5045
Largest weekly change+42.8% (Feb 22, 2023)
Weeks tracked465
Tracking sinceMar 29, 2017

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-37.2%

3Y

-58.7%

5Y

-74.0%

All

-92.5%

Last surveyed Feb 18, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% SOLUTION, manufactured by Lupin Pharmaceuticals Inc., is $0.1204 per ML (NDC 43386002860), effective Feb 18, 2026.

How has the price of CLOBETASOL 0.05% SOLUTION changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% SOLUTION has declined 92.5%. It has been tracked across 465 weekly CMS publications since Mar 29, 2017.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% SOLUTION?

Since Mar 29, 2017, the NADAC for CLOBETASOL 0.05% SOLUTION has ranged from a low of $0.1204 (Feb 18, 2026) to a high of $1.5999 (Apr 12, 2017), with a median of $0.4607 per ML.

Are there cheaper alternatives to CLOBETASOL 0.05% SOLUTION?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CLOBETASOL 0.05% SOLUTION in a comparable dosage form, but none are currently priced below it.

Who manufactures CLOBETASOL 0.05% SOLUTION?

CLOBETASOL 0.05% SOLUTION (NDC 43386002860) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.