Product Information

CLOBETASOL 0.05% SOLUTION is a generic product labeled by Encube Ethicals, Inc., priced at $0.1172 per ML under NDC 21922006127. Its NADAC has been published 104 times since Jul 3, 2024.

CLOBETASOL 0.05% SOLUTION

clobetasol propionate
$0.1172per ML

Strength

.5 mg/mL

NDC

21922006127

Classification

Generic

Dosage Form

SOLUTION

Route

TOPICAL

Last Updated

6/17/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA076977

On Market Since

6/10/2024

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% SOLUTION has been published 104 times since Jul 3, 2024, and over the history we have for it it has declined 33.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1172 per ML
All-time high$0.2506 (Oct 16, 2024)
All-time low$0.1149 (May 20, 2026)
52-week high$0.1917
52-week low$0.1149
Median price$0.1757
Average price$0.1681
Largest weekly change-19.4% (Oct 23, 2024)
Weeks tracked104
Tracking sinceJul 3, 2024

Price History

1W

0.0%

1M

+2.1%

3M

-2.0%

6M

-6.1%

1Y

-35.1%

3Y

N/A

5Y

N/A

All

-33.5%

Generic Alternatives

The matcher finds 5 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 5 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% SOLUTION, manufactured by Encube Ethicals, Inc., is $0.1172 per ML (NDC 21922006127), effective Jun 24, 2026.

How has the price of CLOBETASOL 0.05% SOLUTION changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% SOLUTION has declined 33.5%. It has been tracked across 104 weekly CMS publications since Jul 3, 2024.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% SOLUTION?

Since Jul 3, 2024, the NADAC for CLOBETASOL 0.05% SOLUTION has ranged from a low of $0.1149 (May 20, 2026) to a high of $0.2506 (Oct 16, 2024), with a median of $0.1757 per ML.

Are there cheaper alternatives to CLOBETASOL 0.05% SOLUTION?

5 NADAC-published products share the same active ingredient, strength, and dosage form as CLOBETASOL 0.05% SOLUTION, but none are currently priced below it.

Who manufactures CLOBETASOL 0.05% SOLUTION?

CLOBETASOL 0.05% SOLUTION (NDC 21922006127) is labeled by Encube Ethicals, Inc., and CMS classifies it as a generic product.