Product Information

NAPROXEN SODIUM 220 MG TABLET is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.0669 per EA under NDC 45802049071. Its NADAC has been published 600 times since Jun 11, 2014.

NAPROXEN SODIUM 220 MG TABLET

Naproxen Sodium
$0.0669per EA
OTC

Strength

220 mg/1

NDC

45802049071

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

11/19/2025

Active Ingredients

NAPROXEN SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA074661

On Market Since

4/11/2014

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for NAPROXEN SODIUM 220 MG TABLET has been published 600 times since Jun 11, 2014, and over the history we have for it it has risen 22.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0669 per EA
All-time high$0.0681 (Oct 11, 2023)
All-time low$0.0514 (Apr 21, 2021)
52-week high$0.0669
52-week low$0.0625
Median price$0.0565
Average price$0.0580
Largest weekly change+12.4% (Sep 21, 2022)
Weeks tracked600
Tracking sinceJun 11, 2014

Price History

1W

0.0%

1M

0.0%

3M

0.0%

6M

0.0%

1Y

+7.1%

3Y

+4.0%

5Y

+21.6%

All

+22.5%

Generic Alternatives

The matcher finds 7 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 7 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NAPROXEN SODIUM 220 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN SODIUM 220 MG TABLET, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.0669 per EA (NDC 45802049071), effective Dec 3, 2025.

How has the price of NAPROXEN SODIUM 220 MG TABLET changed over time?

Over the history we have for it, the NADAC for NAPROXEN SODIUM 220 MG TABLET has risen 22.5%. It has been tracked across 600 weekly CMS publications since Jun 11, 2014.

What are the highest and lowest recorded NADAC prices for NAPROXEN SODIUM 220 MG TABLET?

Since Jun 11, 2014, the NADAC for NAPROXEN SODIUM 220 MG TABLET has ranged from a low of $0.0514 (Apr 21, 2021) to a high of $0.0681 (Oct 11, 2023), with a median of $0.0565 per EA.

Are there cheaper alternatives to NAPROXEN SODIUM 220 MG TABLET?

Yes. 7 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ALL DAY PAIN RELIEF 220 MG TAB, is $0.0551 per EA — about 18% below NAPROXEN SODIUM 220 MG TABLET.

Who manufactures NAPROXEN SODIUM 220 MG TABLET?

NAPROXEN SODIUM 220 MG TABLET (NDC 45802049071) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.