Product Information

NAPROXEN SODIUM 220 MG TABLET is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.0669 per EA under NDC 45802049075. Its NADAC has been published 204 times since Sep 28, 2022.

FDA first approved this application on Jan 13, 1997.

NAPROXEN SODIUM 220 MG TABLET

Naproxen Sodium
$0.0669per EA
OTC

Strength

220 mg/1

NDC

45802049075

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

NAPROXEN SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA074661

FDA Approved

1/13/1997

On Market Since

4/11/2014

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for NAPROXEN SODIUM 220 MG TABLET has been published 204 times since Sep 28, 2022, and over the history we have for it it has risen 6.0%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0669 per EA
All-time high$0.0683 (Aug 12, 2026)
All-time low$0.0567 (Apr 17, 2024)
52-week high$0.0683
52-week low$0.0635
Median price$0.0640
Average price$0.0638
Largest weekly change+10.0% (Sep 20, 2023)
Weeks tracked204
Tracking sinceSep 28, 2022

Price History

1W

-2.0%

1M

-2.0%

3M

+3.0%

6M

+2.7%

1Y

+2.9%

3Y

+0.4%

5Y

N/A

All

+6.0%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NAPROXEN SODIUM 220 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN SODIUM 220 MG TABLET, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.0669 per EA (NDC 45802049075), effective Aug 19, 2026.

How has the price of NAPROXEN SODIUM 220 MG TABLET changed over time?

Over the history we have for it, the NADAC for NAPROXEN SODIUM 220 MG TABLET has risen 6.0%. It has been tracked across 204 weekly CMS publications since Sep 28, 2022.

What are the highest and lowest recorded NADAC prices for NAPROXEN SODIUM 220 MG TABLET?

Since Sep 28, 2022, the NADAC for NAPROXEN SODIUM 220 MG TABLET has ranged from a low of $0.0567 (Apr 17, 2024) to a high of $0.0683 (Aug 12, 2026), with a median of $0.0640 per EA.

Are there cheaper alternatives to NAPROXEN SODIUM 220 MG TABLET?

Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ALL DAY PAIN RLF 220 MG CAPLET, is $0.0551 per EA — about 18% below NAPROXEN SODIUM 220 MG TABLET.

Who manufactures NAPROXEN SODIUM 220 MG TABLET?

NAPROXEN SODIUM 220 MG TABLET (NDC 45802049075) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.