Product Information
CYANOCOBALAMIN 500 MCG SPRAY is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $102.1499 per EA under NDC 45802049184. Its NADAC has been published 119 times since Mar 20, 2024.
The High Outlier badge above means this manufacturer's average price in the cyanocobalamin market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
500 ug/1
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802049184
Classification
Generic
Dosage Form
SPRAY
Route
NASAL
Last Updated
6/17/2026
Active Ingredients
CYANOCOBALAMINApproval Type
Generic (ANDA)
FDA Application
ANDA212458On Market Since
12/28/2023
Pharmacological Classes
Price Statistics
The NADAC for CYANOCOBALAMIN 500 MCG SPRAY has been published 119 times since Mar 20, 2024, and over the history we have for it it has declined 24.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $102.1499 per EA |
|---|---|
| All-time high | $134.4279 (Apr 10, 2024) |
| All-time low | $94.0201 (Aug 20, 2025) |
| 52-week high | $124.1779 |
| 52-week low | $94.0201 |
| Median price | $105.7919 |
| Average price | $107.9101 |
| Largest weekly change | -14.0% (Apr 17, 2024) |
| Weeks tracked | 119 |
| Tracking since | Mar 20, 2024 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of CYANOCOBALAMIN 500 MCG SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for CYANOCOBALAMIN 500 MCG SPRAY, manufactured by Padagis Israel Pharmaceuticals Ltd, is $102.1499 per EA (NDC 45802049184), effective Jun 24, 2026.
How has the price of CYANOCOBALAMIN 500 MCG SPRAY changed over time?
Over the history we have for it, the NADAC for CYANOCOBALAMIN 500 MCG SPRAY has declined 24.0%. It has been tracked across 119 weekly CMS publications since Mar 20, 2024.
What are the highest and lowest recorded NADAC prices for CYANOCOBALAMIN 500 MCG SPRAY?
Since Mar 20, 2024, the NADAC for CYANOCOBALAMIN 500 MCG SPRAY has ranged from a low of $94.0201 (Aug 20, 2025) to a high of $134.4279 (Apr 10, 2024), with a median of $105.7919 per EA.
Are there cheaper alternatives to CYANOCOBALAMIN 500 MCG SPRAY?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as CYANOCOBALAMIN 500 MCG SPRAY, but none are currently priced below it.
Who manufactures CYANOCOBALAMIN 500 MCG SPRAY?
CYANOCOBALAMIN 500 MCG SPRAY (NDC 45802049184) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.
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