Product Information
HYDROCORTISONE 2.5% LOTION is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.2110 per ML under NDC 45802093716. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Nov 26, 1985. Its Orange Book therapeutic-equivalence code is AT.
Strength
25 mg/mL
Manufacturer
Padagis Israel Pharmaceuticals LtdNDC
45802093716
Classification
Generic
Dosage Form
LOTION
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
HYDROCORTISONEApproval Type
Generic (ANDA)
FDA Application
ANDA089074FDA Approved
11/26/1985
TE Code
AT
On Market Since
5/23/2008
Pharmacological Classes
Price Statistics
The NADAC for HYDROCORTISONE 2.5% LOTION has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 15.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2110 per ML |
|---|---|
| All-time high | $0.2140 (Mar 11, 2026) |
| All-time low | $0.1420 (Nov 20, 2024) |
| 52-week high | $0.2140 |
| 52-week low | $0.2028 |
| Median price | $0.1838 |
| Average price | $0.1845 |
| Largest weekly change | -28.5% (Nov 20, 2024) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Padagis Israel Pharmaceuticals Ltd manufacturer profile
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Drug market
hydrocortisone market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of HYDROCORTISONE 2.5% LOTION?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE 2.5% LOTION, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.2110 per ML (NDC 45802093716), effective Sep 30, 2026.
How has the price of HYDROCORTISONE 2.5% LOTION changed over time?
Over the history we have for it, the NADAC for HYDROCORTISONE 2.5% LOTION has risen 15.4%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for HYDROCORTISONE 2.5% LOTION?
Since Nov 28, 2013, the NADAC for HYDROCORTISONE 2.5% LOTION has ranged from a low of $0.1420 (Nov 20, 2024) to a high of $0.2140 (Mar 11, 2026), with a median of $0.1838 per ML.
Are there cheaper alternatives to HYDROCORTISONE 2.5% LOTION?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as HYDROCORTISONE 2.5% LOTION in a comparable dosage form, but none are currently priced below it.
Who manufactures HYDROCORTISONE 2.5% LOTION?
HYDROCORTISONE 2.5% LOTION (NDC 45802093716) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.