Product Information

HYDROCORTISONE 2.5% LOTION is a generic product labeled by Padagis Israel Pharmaceuticals Ltd, priced at $0.2323 per ML under NDC 45802093726. Its NADAC has been published 671 times since Nov 28, 2013.

FDA first approved this application on Nov 26, 1985. Its Orange Book therapeutic-equivalence code is AT.

HYDROCORTISONE 2.5% LOTION

hydrocortisone
$0.2323per ML

Strength

25 mg/mL

NDC

45802093726

Classification

Generic

Dosage Form

LOTION

Route

TOPICAL

Effective Date

9/23/2026

Active Ingredients

HYDROCORTISONE

Approval Type

Generic (ANDA)

FDA Application

ANDA089074

FDA Approved

11/26/1985

TE Code

AT

On Market Since

5/23/2008

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for HYDROCORTISONE 2.5% LOTION has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 11.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2323 per ML
All-time high$0.2795 (Oct 14, 2015)
All-time low$0.1666 (Jul 17, 2024)
52-week high$0.2425
52-week low$0.2292
Median price$0.2307
Average price$0.2297
Largest weekly change+36.9% (Jan 19, 2022)
Weeks tracked671
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

+0.7%

3M

-2.8%

6M

-3.6%

1Y

+1.3%

3Y

+4.8%

5Y

-2.7%

All

-11.6%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 9% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 9%

1 alternative • Same active ingredient

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of HYDROCORTISONE 2.5% LOTION?

The current National Average Drug Acquisition Cost (NADAC) for HYDROCORTISONE 2.5% LOTION, manufactured by Padagis Israel Pharmaceuticals Ltd, is $0.2323 per ML (NDC 45802093726), effective Sep 30, 2026.

How has the price of HYDROCORTISONE 2.5% LOTION changed over time?

Over the history we have for it, the NADAC for HYDROCORTISONE 2.5% LOTION has declined 11.6%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for HYDROCORTISONE 2.5% LOTION?

Since Nov 28, 2013, the NADAC for HYDROCORTISONE 2.5% LOTION has ranged from a low of $0.1666 (Jul 17, 2024) to a high of $0.2795 (Oct 14, 2015), with a median of $0.2307 per ML.

Are there cheaper alternatives to HYDROCORTISONE 2.5% LOTION?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCORTISONE 2.5% LOTION, is $0.2110 per ML — about 9% below HYDROCORTISONE 2.5% LOTION.

Who manufactures HYDROCORTISONE 2.5% LOTION?

HYDROCORTISONE 2.5% LOTION (NDC 45802093726) is labeled by Padagis Israel Pharmaceuticals Ltd, and CMS classifies it as a generic product.