Product Information

OMEPRAZOLE DR 20 MG TABLET is a generic product labeled by AmerisourceBergen, priced at $0.3904 per EA under NDC 46122002974. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Dec 4, 2007.

OMEPRAZOLE DR 20 MG TABLET

Omeprazole
$0.3904per EA
OTC

Strength

20 mg/1

Manufacturer

AmerisourceBergen

NDC

46122002974

Classification

Generic

Dosage Form

TABLET, DELAYED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

OMEPRAZOLE

Approval Type

New Drug (NDA)

FDA Application

NDA022032

FDA Approved

12/4/2007

On Market Since

2/27/2008

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Proton Pump Inhibitor
Proton Pump Inhibitors

Price Statistics

The NADAC for OMEPRAZOLE DR 20 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 21.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3904 per EA
All-time high$0.5195 (Feb 12, 2020)
All-time low$0.3668 (May 22, 2024)
52-week high$0.4213
52-week low$0.3737
Median price$0.4797
Average price$0.4662
Largest weekly change+18.4% (Aug 21, 2024)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-0.1%

1M

-0.1%

3M

-2.8%

6M

-2.1%

1Y

+4.5%

3Y

-12.4%

5Y

-16.5%

All

-21.6%

Generic Alternatives

The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of OMEPRAZOLE DR 20 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for OMEPRAZOLE DR 20 MG TABLET, manufactured by AmerisourceBergen, is $0.3904 per EA (NDC 46122002974), effective Aug 19, 2026.

How has the price of OMEPRAZOLE DR 20 MG TABLET changed over time?

Over the history we have for it, the NADAC for OMEPRAZOLE DR 20 MG TABLET has declined 21.6%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for OMEPRAZOLE DR 20 MG TABLET?

Since Nov 28, 2013, the NADAC for OMEPRAZOLE DR 20 MG TABLET has ranged from a low of $0.3668 (May 22, 2024) to a high of $0.5195 (Feb 12, 2020), with a median of $0.4797 per EA.

Are there cheaper alternatives to OMEPRAZOLE DR 20 MG TABLET?

11 manufacturers publish a NADAC-priced product with the same active ingredient and strength as OMEPRAZOLE DR 20 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures OMEPRAZOLE DR 20 MG TABLET?

OMEPRAZOLE DR 20 MG TABLET (NDC 46122002974) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.