Product Information

NAPROXEN SODIUM 220 MG TABLET is a generic product labeled by AmerisourceBergen, priced at $0.0663 per EA under NDC 46122056278. Its NADAC has been published 341 times since Dec 18, 2019.

NAPROXEN SODIUM 220 MG TABLET

Naproxen Sodium
$0.0663per EA
OTC

Strength

220 mg/1

Manufacturer

AmerisourceBergen

NDC

46122056278

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

NAPROXEN SODIUM

Approval Type

Generic (ANDA)

FDA Application

ANDA204872

On Market Since

2/1/2019

Pharmacological Classes

Anti-Inflammatory Agents
Non-Steroidal
Cyclooxygenase Inhibitors
Nonsteroidal Anti-inflammatory Drug

Price Statistics

The NADAC for NAPROXEN SODIUM 220 MG TABLET has been published 341 times since Dec 18, 2019, and over the history we have for it it has risen 19.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0663 per EA
All-time high$0.0681 (Oct 11, 2023)
All-time low$0.0514 (Apr 21, 2021)
52-week high$0.0674
52-week low$0.0625
Median price$0.0616
Average price$0.0602
Largest weekly change+12.4% (Sep 21, 2022)
Weeks tracked341
Tracking sinceDec 18, 2019

Price History

1W

0.0%

1M

+2.1%

3M

+3.3%

6M

-1.6%

1Y

+6.2%

3Y

+3.1%

5Y

+20.5%

All

+19.6%

Generic Alternatives

The matcher finds 7 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 7 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 17% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of NAPROXEN SODIUM 220 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN SODIUM 220 MG TABLET, manufactured by AmerisourceBergen, is $0.0663 per EA (NDC 46122056278), effective Jun 24, 2026.

How has the price of NAPROXEN SODIUM 220 MG TABLET changed over time?

Over the history we have for it, the NADAC for NAPROXEN SODIUM 220 MG TABLET has risen 19.6%. It has been tracked across 341 weekly CMS publications since Dec 18, 2019.

What are the highest and lowest recorded NADAC prices for NAPROXEN SODIUM 220 MG TABLET?

Since Dec 18, 2019, the NADAC for NAPROXEN SODIUM 220 MG TABLET has ranged from a low of $0.0514 (Apr 21, 2021) to a high of $0.0681 (Oct 11, 2023), with a median of $0.0616 per EA.

Are there cheaper alternatives to NAPROXEN SODIUM 220 MG TABLET?

Yes. 7 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, ALL DAY PAIN RELIEF 220 MG TAB, is $0.0551 per EA — about 17% below NAPROXEN SODIUM 220 MG TABLET.

Who manufactures NAPROXEN SODIUM 220 MG TABLET?

NAPROXEN SODIUM 220 MG TABLET (NDC 46122056278) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.