Product Information
NAPROXEN SODIUM 220 MG TABLET is a generic product labeled by AmerisourceBergen, priced at $0.0673 per EA under NDC 46122056278. Its NADAC has been published 355 times since Dec 18, 2019.
FDA first approved this application on Jan 23, 2017.
Strength
220 mg/1
Manufacturer
AmerisourceBergenNDC
46122056278
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
NAPROXEN SODIUMApproval Type
Generic (ANDA)
FDA Application
ANDA204872FDA Approved
1/23/2017
On Market Since
2/1/2019
Pharmacological Classes
Price Statistics
The NADAC for NAPROXEN SODIUM 220 MG TABLET has been published 355 times since Dec 18, 2019, and over the history we have for it it has risen 21.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0673 per EA |
|---|---|
| All-time high | $0.0683 (Aug 12, 2026) |
| All-time low | $0.0514 (Apr 21, 2021) |
| 52-week high | $0.0683 |
| 52-week low | $0.0635 |
| Median price | $0.0617 |
| Average price | $0.0605 |
| Largest weekly change | +12.4% (Sep 21, 2022) |
| Weeks tracked | 355 |
| Tracking since | Dec 18, 2019 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AmerisourceBergen manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Naproxen Sodium market comparison
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Therapeutic class
Nonsteroidal Anti-inflammatory Drug class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of NAPROXEN SODIUM 220 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for NAPROXEN SODIUM 220 MG TABLET, manufactured by AmerisourceBergen, is $0.0673 per EA (NDC 46122056278), effective Sep 30, 2026.
How has the price of NAPROXEN SODIUM 220 MG TABLET changed over time?
Over the history we have for it, the NADAC for NAPROXEN SODIUM 220 MG TABLET has risen 21.4%. It has been tracked across 355 weekly CMS publications since Dec 18, 2019.
What are the highest and lowest recorded NADAC prices for NAPROXEN SODIUM 220 MG TABLET?
Since Dec 18, 2019, the NADAC for NAPROXEN SODIUM 220 MG TABLET has ranged from a low of $0.0514 (Apr 21, 2021) to a high of $0.0683 (Aug 12, 2026), with a median of $0.0617 per EA.
Are there cheaper alternatives to NAPROXEN SODIUM 220 MG TABLET?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ALL DAY PAIN RELIEF 220 MG TAB, is $0.0551 per EA — about 18% below NAPROXEN SODIUM 220 MG TABLET.
Who manufactures NAPROXEN SODIUM 220 MG TABLET?
NAPROXEN SODIUM 220 MG TABLET (NDC 46122056278) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.