Product Information

ANTI-DIARRHEAL 2 MG SOFTGEL is a generic product labeled by AmerisourceBergen, priced at $0.1362 per EA under NDC 46122058162. Its NADAC has been published 365 times since Aug 28, 2019.

FDA first approved this application on Aug 4, 2005.

ANTI-DIARRHEAL 2 MG SOFTGEL

LOPERAMIDE HYDROCHLORIDE
$0.1362per EA
OTC

Strength

2 mg/1

Manufacturer

AmerisourceBergen

NDC

46122058162

Classification

Generic

Dosage Form

CAPSULE, LIQUID FILLED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

LOPERAMIDE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA021855

FDA Approved

8/4/2005

On Market Since

2/15/2019

Pharmacological Classes

Opioid Agonist
Opioid Agonists

Price Statistics

The NADAC for ANTI-DIARRHEAL 2 MG SOFTGEL has been published 365 times since Aug 28, 2019, and over the history we have for it it has risen 14.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1362 per EA
All-time high$0.1625 (Mar 11, 2020)
All-time low$0.1194 (Aug 28, 2019)
52-week high$0.1362
52-week low$0.1329
Median price$0.1396
Average price$0.1406
Largest weekly change-13.9% (Mar 18, 2020)
Weeks tracked365
Tracking sinceAug 28, 2019

Price History

1W

+1.2%

1M

+1.2%

3M

+1.8%

6M

+1.7%

1Y

+0.3%

3Y

-5.2%

5Y

-5.7%

All

+14.1%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 59% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ANTI-DIARRHEAL 2 MG SOFTGEL?

The current National Average Drug Acquisition Cost (NADAC) for ANTI-DIARRHEAL 2 MG SOFTGEL, manufactured by AmerisourceBergen, is $0.1362 per EA (NDC 46122058162), effective Aug 19, 2026.

How has the price of ANTI-DIARRHEAL 2 MG SOFTGEL changed over time?

Over the history we have for it, the NADAC for ANTI-DIARRHEAL 2 MG SOFTGEL has risen 14.1%. It has been tracked across 365 weekly CMS publications since Aug 28, 2019.

What are the highest and lowest recorded NADAC prices for ANTI-DIARRHEAL 2 MG SOFTGEL?

Since Aug 28, 2019, the NADAC for ANTI-DIARRHEAL 2 MG SOFTGEL has ranged from a low of $0.1194 (Aug 28, 2019) to a high of $0.1625 (Mar 11, 2020), with a median of $0.1396 per EA.

Are there cheaper alternatives to ANTI-DIARRHEAL 2 MG SOFTGEL?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, LOPERAMIDE 2 MG CAPSULE, is $0.0565 per EA — about 59% below ANTI-DIARRHEAL 2 MG SOFTGEL.

Who manufactures ANTI-DIARRHEAL 2 MG SOFTGEL?

ANTI-DIARRHEAL 2 MG SOFTGEL (NDC 46122058162) is labeled by AmerisourceBergen, and CMS classifies it as a generic product.