Product Information
SM NASAL SPRAY 0.05% is a generic product labeled by Strategic Sourcing Services LLC, priced at $0.0763 per ML under NDC 49348002827. Its NADAC has been published 658 times since Nov 28, 2013.
Strength
.05 mg/100mL
Manufacturer
Strategic Sourcing Services LLCNDC
49348002827
Classification
Generic
Dosage Form
SPRAY
Route
NASAL
Effective Date
6/17/2026
Active Ingredients
OXYMETAZOLINE HYDROCHLORIDEApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
6/27/2003
Pharmacological Classes
Price Statistics
The NADAC for SM NASAL SPRAY 0.05% has been published 658 times since Nov 28, 2013, and over the history we have for it it has risen 42.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0763 per ML |
|---|---|
| All-time high | $0.0820 (Jul 12, 2023) |
| All-time low | $0.0503 (Sep 17, 2014) |
| 52-week high | $0.0778 |
| 52-week low | $0.0706 |
| Median price | $0.0595 |
| Average price | $0.0626 |
| Largest weekly change | +24.6% (Jan 18, 2023) |
| Weeks tracked | 658 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
N/A
6M
+3.5%
1Y
+4.1%
3Y
+9.4%
5Y
+28.1%
All
+42.2%
Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Strategic Sourcing Services LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
oxymetazoline hydrochloride market comparison
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Therapeutic class
Vasoconstrictor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of SM NASAL SPRAY 0.05%?
The current National Average Drug Acquisition Cost (NADAC) for SM NASAL SPRAY 0.05%, manufactured by Strategic Sourcing Services LLC, is $0.0763 per ML (NDC 49348002827), effective Jul 1, 2026.
How has the price of SM NASAL SPRAY 0.05% changed over time?
Over the history we have for it, the NADAC for SM NASAL SPRAY 0.05% has risen 42.2%. It has been tracked across 658 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SM NASAL SPRAY 0.05%?
Since Nov 28, 2013, the NADAC for SM NASAL SPRAY 0.05% has ranged from a low of $0.0503 (Sep 17, 2014) to a high of $0.0820 (Jul 12, 2023), with a median of $0.0595 per ML.
Are there cheaper alternatives to SM NASAL SPRAY 0.05%?
Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NASAL SPRAY 0.05%, is $0.0625 per ML — about 18% below SM NASAL SPRAY 0.05%.
Who manufactures SM NASAL SPRAY 0.05%?
SM NASAL SPRAY 0.05% (NDC 49348002827) is labeled by Strategic Sourcing Services LLC, and CMS classifies it as a generic product.