Product Information

SM NASAL SPRAY 0.05% is a generic product labeled by Strategic Sourcing Services LLC, priced at $0.0763 per ML under NDC 49348002827. Its NADAC has been published 658 times since Nov 28, 2013.

SM NASAL SPRAY 0.05%

oxymetazoline hydrochloride
$0.0763per ML
Discontinued
OTC

Strength

.05 mg/100mL

NDC

49348002827

Classification

Generic

Dosage Form

SPRAY

Route

NASAL

Effective Date

6/17/2026

Active Ingredients

OXYMETAZOLINE HYDROCHLORIDE

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

6/27/2003

Pharmacological Classes

Imidazolines
Increased Sympathetic Activity
Vasoconstriction
Vasoconstrictor

Price Statistics

The NADAC for SM NASAL SPRAY 0.05% has been published 658 times since Nov 28, 2013, and over the history we have for it it has risen 42.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0763 per ML
All-time high$0.0820 (Jul 12, 2023)
All-time low$0.0503 (Sep 17, 2014)
52-week high$0.0778
52-week low$0.0706
Median price$0.0595
Average price$0.0626
Largest weekly change+24.6% (Jan 18, 2023)
Weeks tracked658
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

-0.2%

6M

+8.1%

1Y

+4.7%

3Y

+4.3%

5Y

+19.9%

All

+42.2%

Last surveyed Jul 1, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SM NASAL SPRAY 0.05%?

The current National Average Drug Acquisition Cost (NADAC) for SM NASAL SPRAY 0.05%, manufactured by Strategic Sourcing Services LLC, is $0.0763 per ML (NDC 49348002827), effective Jul 1, 2026.

How has the price of SM NASAL SPRAY 0.05% changed over time?

Over the history we have for it, the NADAC for SM NASAL SPRAY 0.05% has risen 42.2%. It has been tracked across 658 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for SM NASAL SPRAY 0.05%?

Since Nov 28, 2013, the NADAC for SM NASAL SPRAY 0.05% has ranged from a low of $0.0503 (Sep 17, 2014) to a high of $0.0820 (Jul 12, 2023), with a median of $0.0595 per ML.

Are there cheaper alternatives to SM NASAL SPRAY 0.05%?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, NASAL SPRAY 0.05%, is $0.0625 per ML — about 18% below SM NASAL SPRAY 0.05%.

Who manufactures SM NASAL SPRAY 0.05%?

SM NASAL SPRAY 0.05% (NDC 49348002827) is labeled by Strategic Sourcing Services LLC, and CMS classifies it as a generic product.