Product Information

METFORMIN ER 500 MG GASTRC-TB is a generic product labeled by ScieGen Pharmaceuticals, Inc., priced at $0.2619 per EA under NDC 50228044501. Its NADAC has been published 260 times since Sep 1, 2021.

FDA first approved this application on Apr 16, 2021. Its Orange Book therapeutic-equivalence code is AB3 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METFORMIN ER 500 MG GASTRC-TB

Metformin Hydrochloride Extended-Release Tablets
$0.2619per EA

Strength

500 mg/1

NDC

50228044501

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METFORMIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA213334

FDA Approved

4/16/2021

TE Code

AB3

On Market Since

4/16/2021

Pharmacological Classes

Biguanide
Biguanides

Price Statistics

The NADAC for METFORMIN ER 500 MG GASTRC-TB has been published 260 times since Sep 1, 2021, and over the history we have for it it has declined 87.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2619 per EA
All-time high$2.7019 (May 10, 2023)
All-time low$0.2619 (Aug 19, 2026)
52-week high$0.3965
52-week low$0.2619
Median price$0.6048
Average price$1.0915
Largest weekly change+107.3% (Feb 23, 2022)
Weeks tracked260
Tracking sinceSep 1, 2021

Price History

1W

-0.0%

1M

-0.0%

3M

-8.4%

6M

-9.6%

1Y

-14.7%

3Y

-56.7%

5Y

N/A

All

-87.1%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 47% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 47%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of METFORMIN ER 500 MG GASTRC-TB?

The current National Average Drug Acquisition Cost (NADAC) for METFORMIN ER 500 MG GASTRC-TB, manufactured by ScieGen Pharmaceuticals, Inc., is $0.2619 per EA (NDC 50228044501), effective Aug 19, 2026.

How has the price of METFORMIN ER 500 MG GASTRC-TB changed over time?

Over the history we have for it, the NADAC for METFORMIN ER 500 MG GASTRC-TB has declined 87.1%. It has been tracked across 260 weekly CMS publications since Sep 1, 2021.

What are the highest and lowest recorded NADAC prices for METFORMIN ER 500 MG GASTRC-TB?

Since Sep 1, 2021, the NADAC for METFORMIN ER 500 MG GASTRC-TB has ranged from a low of $0.2619 (Aug 19, 2026) to a high of $2.7019 (May 10, 2023), with a median of $0.6048 per EA.

Are there cheaper alternatives to METFORMIN ER 500 MG GASTRC-TB?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN ER 500 MG OSMOTIC TB, is $0.1383 per EA — about 47% below METFORMIN ER 500 MG GASTRC-TB.

Who manufactures METFORMIN ER 500 MG GASTRC-TB?

METFORMIN ER 500 MG GASTRC-TB (NDC 50228044501) is labeled by ScieGen Pharmaceuticals, Inc., and CMS classifies it as a generic product.