Product Information

METFORMIN ER 500 MG OSMOTIC TB is a generic product labeled by ScieGen Pharmaceuticals, Inc., priced at $0.1383 per EA under NDC 50228050360. Its NADAC has been published 193 times since Dec 14, 2022.

FDA first approved this application on Feb 22, 2022. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METFORMIN ER 500 MG OSMOTIC TB

Metformin Hydrochloride Extended-Release Tablets
$0.1383per EA

Strength

500 mg/1

NDC

50228050360

Classification

Generic

Dosage Form

TABLET, FILM COATED, EXTENDED RELEASE

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

METFORMIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA214629

FDA Approved

2/22/2022

TE Code

AB2

On Market Since

2/22/2022

Pharmacological Classes

Biguanide
Biguanides

Price Statistics

The NADAC for METFORMIN ER 500 MG OSMOTIC TB has been published 193 times since Dec 14, 2022, and over the history we have for it it has declined 77.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1383 per EA
All-time high$0.6331 (Feb 15, 2023)
All-time low$0.1017 (Apr 22, 2026)
52-week high$0.1722
52-week low$0.1017
Median price$0.1450
Average price$0.1898
Largest weekly change-77.1% (Feb 22, 2023)
Weeks tracked193
Tracking sinceDec 14, 2022

Price History

1W

+18.9%

1M

+18.9%

3M

+31.4%

6M

+24.0%

1Y

-5.0%

3Y

-34.4%

5Y

N/A

All

-77.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METFORMIN ER 500 MG OSMOTIC TB?

The current National Average Drug Acquisition Cost (NADAC) for METFORMIN ER 500 MG OSMOTIC TB, manufactured by ScieGen Pharmaceuticals, Inc., is $0.1383 per EA (NDC 50228050360), effective Aug 19, 2026.

How has the price of METFORMIN ER 500 MG OSMOTIC TB changed over time?

Over the history we have for it, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has declined 77.9%. It has been tracked across 193 weekly CMS publications since Dec 14, 2022.

What are the highest and lowest recorded NADAC prices for METFORMIN ER 500 MG OSMOTIC TB?

Since Dec 14, 2022, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has ranged from a low of $0.1017 (Apr 22, 2026) to a high of $0.6331 (Feb 15, 2023), with a median of $0.1450 per EA.

Are there cheaper alternatives to METFORMIN ER 500 MG OSMOTIC TB?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METFORMIN ER 500 MG OSMOTIC TB in a comparable dosage form, but none are currently priced below it.

Who manufactures METFORMIN ER 500 MG OSMOTIC TB?

METFORMIN ER 500 MG OSMOTIC TB (NDC 50228050360) is labeled by ScieGen Pharmaceuticals, Inc., and CMS classifies it as a generic product.