Product Information
AMITRIPTYLINE HCL 25 MG TAB is a generic product labeled by AvPAK, priced at $0.0524 per EA under NDC 50268003815. Its NADAC has been published 142 times since Oct 11, 2023.
The Low Outlier badge above means this manufacturer's average price in the Amitriptyline Hydrochloride market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25 mg/1
Manufacturer
AvPAKNDC
50268003815
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
AMITRIPTYLINE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA214548On Market Since
6/6/2023
Pharmacological Classes
Price Statistics
The NADAC for AMITRIPTYLINE HCL 25 MG TAB has been published 142 times since Oct 11, 2023, and over the history we have for it it has declined 15.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0524 per EA |
|---|---|
| All-time high | $0.0703 (Apr 10, 2024) |
| All-time low | $0.0411 (Nov 20, 2024) |
| 52-week high | $0.0566 |
| 52-week low | $0.0523 |
| Median price | $0.0556 |
| Average price | $0.0562 |
| Largest weekly change | -27.3% (Nov 20, 2024) |
| Weeks tracked | 142 |
| Tracking since | Oct 11, 2023 |
Generic Alternatives
The matcher finds 11 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of AMITRIPTYLINE HCL 25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for AMITRIPTYLINE HCL 25 MG TAB, manufactured by AvPAK, is $0.0524 per EA (NDC 50268003815), effective Jun 24, 2026.
How has the price of AMITRIPTYLINE HCL 25 MG TAB changed over time?
Over the history we have for it, the NADAC for AMITRIPTYLINE HCL 25 MG TAB has declined 15.9%. It has been tracked across 142 weekly CMS publications since Oct 11, 2023.
What are the highest and lowest recorded NADAC prices for AMITRIPTYLINE HCL 25 MG TAB?
Since Oct 11, 2023, the NADAC for AMITRIPTYLINE HCL 25 MG TAB has ranged from a low of $0.0411 (Nov 20, 2024) to a high of $0.0703 (Apr 10, 2024), with a median of $0.0556 per EA.
Are there cheaper alternatives to AMITRIPTYLINE HCL 25 MG TAB?
11 NADAC-published products share the same active ingredient, strength, and dosage form as AMITRIPTYLINE HCL 25 MG TAB, but none are currently priced below it.
Who manufactures AMITRIPTYLINE HCL 25 MG TAB?
AMITRIPTYLINE HCL 25 MG TAB (NDC 50268003815) is labeled by AvPAK, and CMS classifies it as a generic product.
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