Product Information

ACETAZOLAMIDE 250 MG TABLET is a generic product labeled by AvPAK, priced at $0.1315 per EA under NDC 50268005415. Its NADAC has been published 306 times since Oct 14, 2020.

FDA first approved this application on Nov 20, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ACETAZOLAMIDE 250 MG TABLET

Acetazolamide
$0.1315per EA

Strength

250 mg/1

Manufacturer

AvPAK

NDC

50268005415

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ACETAZOLAMIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA209734

FDA Approved

11/20/2017

TE Code

AB

On Market Since

7/7/2020

Pharmacological Classes

Carbonic Anhydrase Inhibitor
Carbonic Anhydrase Inhibitors
Sulfonamides

Price Statistics

The NADAC for ACETAZOLAMIDE 250 MG TABLET has been published 306 times since Oct 14, 2020, and over the history we have for it it has declined 84.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1315 per EA
All-time high$0.8260 (Oct 14, 2020)
All-time low$0.1231 (Dec 17, 2025)
52-week high$0.1489
52-week low$0.1231
Median price$0.1979
Average price$0.2621
Largest weekly change-52.8% (Aug 18, 2021)
Weeks tracked306
Tracking sinceOct 14, 2020

Price History

1W

-1.1%

1M

-1.1%

3M

-5.0%

6M

-2.8%

1Y

-9.5%

3Y

-37.3%

5Y

-52.6%

All

-84.1%

Generic Alternatives

The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ACETAZOLAMIDE 250 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ACETAZOLAMIDE 250 MG TABLET, manufactured by AvPAK, is $0.1315 per EA (NDC 50268005415), effective Aug 19, 2026.

How has the price of ACETAZOLAMIDE 250 MG TABLET changed over time?

Over the history we have for it, the NADAC for ACETAZOLAMIDE 250 MG TABLET has declined 84.1%. It has been tracked across 306 weekly CMS publications since Oct 14, 2020.

What are the highest and lowest recorded NADAC prices for ACETAZOLAMIDE 250 MG TABLET?

Since Oct 14, 2020, the NADAC for ACETAZOLAMIDE 250 MG TABLET has ranged from a low of $0.1231 (Dec 17, 2025) to a high of $0.8260 (Oct 14, 2020), with a median of $0.1979 per EA.

Are there cheaper alternatives to ACETAZOLAMIDE 250 MG TABLET?

7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ACETAZOLAMIDE 250 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures ACETAZOLAMIDE 250 MG TABLET?

ACETAZOLAMIDE 250 MG TABLET (NDC 50268005415) is labeled by AvPAK, and CMS classifies it as a generic product.