Product Information
ACYCLOVIR 400 MG TABLET is a generic product labeled by AvPAK, priced at $0.0985 per EA under NDC 50268006115. Its NADAC has been published 458 times since Nov 15, 2017.
FDA first approved this application on Apr 30, 1999. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
400 mg/1
Manufacturer
AvPAKNDC
50268006115
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACYCLOVIRApproval Type
Generic (ANDA)
FDA Application
ANDA075382FDA Approved
4/30/1999
TE Code
AB
On Market Since
3/16/2011
Pharmacological Classes
Price Statistics
The NADAC for ACYCLOVIR 400 MG TABLET has been published 458 times since Nov 15, 2017, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0985 per EA |
|---|---|
| All-time high | $0.1245 (Jan 13, 2021) |
| All-time low | $0.0689 (Nov 20, 2024) |
| 52-week high | $0.1007 |
| 52-week low | $0.0912 |
| Median price | $0.0948 |
| Average price | $0.0950 |
| Largest weekly change | -28.6% (Nov 20, 2024) |
| Weeks tracked | 458 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 21% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of ACYCLOVIR 400 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ACYCLOVIR 400 MG TABLET, manufactured by AvPAK, is $0.0985 per EA (NDC 50268006115), effective Aug 19, 2026.
How has the price of ACYCLOVIR 400 MG TABLET changed over time?
Over the history we have for it, the NADAC for ACYCLOVIR 400 MG TABLET has held within roughly two percent of its current level. It has been tracked across 458 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for ACYCLOVIR 400 MG TABLET?
Since Nov 15, 2017, the NADAC for ACYCLOVIR 400 MG TABLET has ranged from a low of $0.0689 (Nov 20, 2024) to a high of $0.1245 (Jan 13, 2021), with a median of $0.0948 per EA.
Are there cheaper alternatives to ACYCLOVIR 400 MG TABLET?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ACYCLOVIR 400 MG TABLET, is $0.0779 per EA — about 21% below ACYCLOVIR 400 MG TABLET.
Who manufactures ACYCLOVIR 400 MG TABLET?
ACYCLOVIR 400 MG TABLET (NDC 50268006115) is labeled by AvPAK, and CMS classifies it as a generic product.