Product Information
BUPROPION HCL 75 MG TABLET is a generic product labeled by AvPAK, priced at $0.0928 per EA under NDC 50268014215. Its NADAC has been published 464 times since Nov 15, 2017.
FDA first approved this application on Jan 17, 2006. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
75 mg/1
Manufacturer
AvPAKNDC
50268014215
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
BUPROPION HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA076143FDA Approved
1/17/2006
TE Code
AB
On Market Since
8/2/2017
Pharmacological Classes
Price Statistics
The NADAC for BUPROPION HCL 75 MG TABLET has been published 464 times since Nov 15, 2017, and over the history we have for it it has declined 66.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0928 per EA |
|---|---|
| All-time high | $0.3016 (Mar 14, 2018) |
| All-time low | $0.0862 (Nov 20, 2024) |
| 52-week high | $0.0991 |
| 52-week low | $0.0928 |
| Median price | $0.1226 |
| Average price | $0.1523 |
| Largest weekly change | +21.8% (Oct 17, 2018) |
| Weeks tracked | 464 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
AvPAK manufacturer profile
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Drug market
Bupropion Hydrochloride market comparison
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Therapeutic class
Aminoketone class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BUPROPION HCL 75 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL 75 MG TABLET, manufactured by AvPAK, is $0.0928 per EA (NDC 50268014215), effective Sep 30, 2026.
How has the price of BUPROPION HCL 75 MG TABLET changed over time?
Over the history we have for it, the NADAC for BUPROPION HCL 75 MG TABLET has declined 66.2%. It has been tracked across 464 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for BUPROPION HCL 75 MG TABLET?
Since Nov 15, 2017, the NADAC for BUPROPION HCL 75 MG TABLET has ranged from a low of $0.0862 (Nov 20, 2024) to a high of $0.3016 (Mar 14, 2018), with a median of $0.1226 per EA.
Are there cheaper alternatives to BUPROPION HCL 75 MG TABLET?
7 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BUPROPION HCL 75 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures BUPROPION HCL 75 MG TABLET?
BUPROPION HCL 75 MG TABLET (NDC 50268014215) is labeled by AvPAK, and CMS classifies it as a generic product.