Product Information

BUPROPION HCL SR 100 MG TABLET is a generic product labeled by Epic Pharma LLC, priced at $0.0752 per EA under NDC 42806041005. Its NADAC has been published 221 times since Apr 6, 2022.

BUPROPION HCL SR 100 MG TABLET

BUPROPION HYDROCHLORIDE
$0.0752per EA

Strength

100 mg/1

Manufacturer

Epic Pharma LLC

NDC

42806041005

Classification

Generic

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

BUPROPION HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075932

On Market Since

12/15/2021

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors

Price Statistics

The NADAC for BUPROPION HCL SR 100 MG TABLET has been published 221 times since Apr 6, 2022, and over the history we have for it it has declined 33.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0752 per EA
All-time high$0.1153 (Oct 11, 2023)
All-time low$0.0639 (Oct 22, 2025)
52-week high$0.0923
52-week low$0.0639
Median price$0.0951
Average price$0.0921
Largest weekly change+30.2% (Jun 19, 2024)
Weeks tracked221
Tracking sinceApr 6, 2022

Price History

1W

0.0%

1M

+0.3%

3M

+11.3%

6M

+7.5%

1Y

-17.5%

3Y

-27.7%

5Y

N/A

All

-33.3%

Generic Alternatives

The matcher finds 2 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 2 manufacturers (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of BUPROPION HCL SR 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for BUPROPION HCL SR 100 MG TABLET, manufactured by Epic Pharma LLC, is $0.0752 per EA (NDC 42806041005), effective Jun 24, 2026.

How has the price of BUPROPION HCL SR 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for BUPROPION HCL SR 100 MG TABLET has declined 33.3%. It has been tracked across 221 weekly CMS publications since Apr 6, 2022.

What are the highest and lowest recorded NADAC prices for BUPROPION HCL SR 100 MG TABLET?

Since Apr 6, 2022, the NADAC for BUPROPION HCL SR 100 MG TABLET has ranged from a low of $0.0639 (Oct 22, 2025) to a high of $0.1153 (Oct 11, 2023), with a median of $0.0951 per EA.

Are there cheaper alternatives to BUPROPION HCL SR 100 MG TABLET?

2 NADAC-published products share the same active ingredient, strength, and dosage form as BUPROPION HCL SR 100 MG TABLET, but none are currently priced below it.

Who manufactures BUPROPION HCL SR 100 MG TABLET?

BUPROPION HCL SR 100 MG TABLET (NDC 42806041005) is labeled by Epic Pharma LLC, and CMS classifies it as a generic product.