Product Information

CHLORTHALIDONE 25 MG TABLET is a generic product labeled by AvPAK, priced at $0.0840 per EA under NDC 50268016715. Its NADAC has been published 335 times since Mar 25, 2020.

FDA first approved this application on Oct 12, 2018. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The Low Outlier badge above means this manufacturer's average price in the CHLORTHALIDONE market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

CHLORTHALIDONE 25 MG TABLET

CHLORTHALIDONE
$0.0840per EA
Low Outlier

Strength

25 mg/1

Manufacturer

AvPAK

NDC

50268016715

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CHLORTHALIDONE

Approval Type

Generic (ANDA)

FDA Application

ANDA210742

FDA Approved

10/12/2018

TE Code

AB

On Market Since

11/12/2019

Pharmacological Classes

Increased Diuresis
Thiazide-like Diuretic

Price Statistics

The NADAC for CHLORTHALIDONE 25 MG TABLET has been published 335 times since Mar 25, 2020, and over the history we have for it it has declined 76.4%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0840 per EA
All-time high$0.3562 (Apr 15, 2020)
All-time low$0.0703 (Jul 17, 2024)
52-week high$0.0901
52-week low$0.0833
Median price$0.1029
Average price$0.1405
Largest weekly change+30.9% (Aug 21, 2024)
Weeks tracked335
Tracking sinceMar 25, 2020

Price History

1W

-1.0%

1M

-1.0%

3M

-5.5%

6M

+0.8%

1Y

-3.2%

3Y

-14.0%

5Y

-50.7%

All

-76.4%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CHLORTHALIDONE 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for CHLORTHALIDONE 25 MG TABLET, manufactured by AvPAK, is $0.0840 per EA (NDC 50268016715), effective Aug 19, 2026.

How has the price of CHLORTHALIDONE 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for CHLORTHALIDONE 25 MG TABLET has declined 76.4%. It has been tracked across 335 weekly CMS publications since Mar 25, 2020.

What are the highest and lowest recorded NADAC prices for CHLORTHALIDONE 25 MG TABLET?

Since Mar 25, 2020, the NADAC for CHLORTHALIDONE 25 MG TABLET has ranged from a low of $0.0703 (Jul 17, 2024) to a high of $0.3562 (Apr 15, 2020), with a median of $0.1029 per EA.

Are there cheaper alternatives to CHLORTHALIDONE 25 MG TABLET?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CHLORTHALIDONE 25 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures CHLORTHALIDONE 25 MG TABLET?

CHLORTHALIDONE 25 MG TABLET (NDC 50268016715) is labeled by AvPAK, and CMS classifies it as a generic product.