Product Information
HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET is a generic product labeled by AvPAK, priced at $0.1522 per EA under NDC 50268040215. Its NADAC has been published 458 times since Nov 15, 2017.
FDA first approved this application on Aug 25, 2006. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 10 mg/1; mg/1
Manufacturer
AvPAKNDC
50268040215
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; HYDROCODONE BITARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA040736FDA Approved
8/25/2006
TE Code
AA
On Market Since
9/15/2014
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has been published 458 times since Nov 15, 2017, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1522 per EA |
|---|---|
| All-time high | $0.1684 (Jul 10, 2024) |
| All-time low | $0.1075 (Nov 20, 2019) |
| 52-week high | $0.1613 |
| 52-week low | $0.1522 |
| Median price | $0.1366 |
| Average price | $0.1388 |
| Largest weekly change | +17.4% (Jun 19, 2024) |
| Weeks tracked | 458 |
| Tracking since | Nov 15, 2017 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 12% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET, manufactured by AvPAK, is $0.1522 per EA (NDC 50268040215), effective Aug 19, 2026.
How has the price of HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has held within roughly two percent of its current level. It has been tracked across 458 weekly CMS publications since Nov 15, 2017.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
Since Nov 15, 2017, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has ranged from a low of $0.1075 (Nov 20, 2019) to a high of $0.1684 (Jul 10, 2024), with a median of $0.1366 per EA.
Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET, is $0.1347 per EA — about 12% below HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET.
Who manufactures HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET (NDC 50268040215) is labeled by AvPAK, and CMS classifies it as a generic product.