Product Information
HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $0.1522 per EA under NDC 42858020350. Its NADAC has been published 536 times since May 18, 2016.
FDA first approved this application on Apr 12, 2016. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 10 mg/1; mg/1
Manufacturer
Rhodes Pharmaceuticals L.P.NDC
42858020350
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; HYDROCODONE BITARTRATEApproval Type
Generic (ANDA)
FDA Application
ANDA202991FDA Approved
4/12/2016
TE Code
AA
On Market Since
4/12/2016
Pharmacological Classes
Price Statistics
The NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has been published 536 times since May 18, 2016, and over the history we have for it it has declined 16.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1522 per EA |
|---|---|
| All-time high | $0.1992 (Oct 12, 2016) |
| All-time low | $0.1075 (Nov 20, 2019) |
| 52-week high | $0.1613 |
| 52-week low | $0.1522 |
| Median price | $0.1392 |
| Average price | $0.1440 |
| Largest weekly change | +17.4% (Jun 19, 2024) |
| Weeks tracked | 536 |
| Tracking since | May 18, 2016 |
Generic Alternatives
The matcher finds 12 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 12% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET, manufactured by Rhodes Pharmaceuticals L.P., is $0.1522 per EA (NDC 42858020350), effective Aug 19, 2026.
How has the price of HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET changed over time?
Over the history we have for it, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has declined 16.9%. It has been tracked across 536 weekly CMS publications since May 18, 2016.
What are the highest and lowest recorded NADAC prices for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
Since May 18, 2016, the NADAC for HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET has ranged from a low of $0.1075 (Nov 20, 2019) to a high of $0.1992 (Oct 12, 2016), with a median of $0.1392 per EA.
Are there cheaper alternatives to HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
Yes. 12 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET, is $0.1347 per EA — about 12% below HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET.
Who manufactures HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET?
HYDROCODONE-ACETAMINOPHEN 10-325 MG TABLET (NDC 42858020350) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.