Product Information
OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET is a generic product labeled by AvPAK, priced at $0.2360 per EA under NDC 50268064615. Its NADAC has been published 402 times since Dec 12, 2018.
FDA first approved this application on Nov 27, 2007. Its Orange Book therapeutic-equivalence code is AA.
Strength
325; 10 mg/1; mg/1
Manufacturer
AvPAKNDC
50268064615
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
ACETAMINOPHEN; OXYCODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA040778FDA Approved
11/27/2007
TE Code
AA
On Market Since
7/9/2018
Pharmacological Classes
Price Statistics
The NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has been published 402 times since Dec 12, 2018, and over the history we have for it it has declined 21.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2360 per EA |
|---|---|
| All-time high | $0.3021 (Aug 14, 2019) |
| All-time low | $0.1580 (Sep 22, 2021) |
| 52-week high | $0.2515 |
| 52-week low | $0.2292 |
| Median price | $0.2199 |
| Average price | $0.2220 |
| Largest weekly change | -22.1% (Nov 20, 2024) |
| Weeks tracked | 402 |
| Tracking since | Dec 12, 2018 |
Generic Alternatives
The matcher finds 11 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 24% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET, manufactured by AvPAK, is $0.2360 per EA (NDC 50268064615), effective Aug 19, 2026.
How has the price of OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET changed over time?
Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has declined 21.6%. It has been tracked across 402 weekly CMS publications since Dec 12, 2018.
What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
Since Dec 12, 2018, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET has ranged from a low of $0.1580 (Sep 22, 2021) to a high of $0.3021 (Aug 14, 2019), with a median of $0.2199 per EA.
Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
Yes. 11 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET, is $0.1796 per EA — about 24% below OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET.
Who manufactures OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET?
OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET (NDC 50268064615) is labeled by AvPAK, and CMS classifies it as a generic product.