Product Information
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB is a generic product labeled by Rhodes Pharmaceuticals L.P., priced at $0.2307 per EA under NDC 42858010450. Its NADAC has been published 606 times since Nov 19, 2014.
Strength
325; 10 mg/1; mg/1
Manufacturer
Rhodes Pharmaceuticals L.P.NDC
42858010450
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Last Updated
6/17/2026
Active Ingredients
ACETAMINOPHEN; OXYCODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA201278On Market Since
8/28/2014
Pharmacological Classes
Price Statistics
The NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB has been published 606 times since Nov 19, 2014, and over the history we have for it it has declined 71.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2307 per EA |
|---|---|
| All-time high | $0.7962 (Dec 10, 2014) |
| All-time low | $0.1580 (Sep 22, 2021) |
| 52-week high | $0.2716 |
| 52-week low | $0.2292 |
| Median price | $0.2500 |
| Average price | $0.3324 |
| Largest weekly change | -22.1% (Nov 20, 2024) |
| Weeks tracked | 606 |
| Tracking since | Nov 19, 2014 |
Generic Alternatives
The matcher finds 12 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 10 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 22% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB, manufactured by Rhodes Pharmaceuticals L.P., is $0.2307 per EA (NDC 42858010450), effective Jun 24, 2026.
How has the price of OXYCODONE-ACETAMINOPHEN 10-325 MG TAB changed over time?
Over the history we have for it, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB has declined 71.0%. It has been tracked across 606 weekly CMS publications since Nov 19, 2014.
What are the highest and lowest recorded NADAC prices for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
Since Nov 19, 2014, the NADAC for OXYCODONE-ACETAMINOPHEN 10-325 MG TAB has ranged from a low of $0.1580 (Sep 22, 2021) to a high of $0.7962 (Dec 10, 2014), with a median of $0.2500 per EA.
Are there cheaper alternatives to OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
Yes. 12 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, OXYCODONE-ACETAMINOPHEN 10-325 MG TABLET, is $0.1796 per EA — about 22% below OXYCODONE-ACETAMINOPHEN 10-325 MG TAB.
Who manufactures OXYCODONE-ACETAMINOPHEN 10-325 MG TAB?
OXYCODONE-ACETAMINOPHEN 10-325 MG TAB (NDC 42858010450) is labeled by Rhodes Pharmaceuticals L.P., and CMS classifies it as a generic product.
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