Product Information
LEUCOVORIN CALCIUM 5 MG TAB is a generic product labeled by Ingenus Pharmaceuticals LLC, priced at $0.3300 per EA under NDC 50742018130. Its NADAC has been published 309 times since Nov 4, 2020.
FDA first approved this application on Jul 30, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Ingenus Pharmaceuticals LLCNDC
50742018130
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LEUCOVORIN CALCIUMApproval Type
Generic (ANDA)
FDA Application
ANDA211132FDA Approved
7/30/2020
TE Code
AB
On Market Since
7/30/2020
Pharmacological Classes
Price Statistics
The NADAC for LEUCOVORIN CALCIUM 5 MG TAB has been published 309 times since Nov 4, 2020, and over the history we have for it it has declined 62.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3300 per EA |
|---|---|
| All-time high | $0.8875 (Sep 15, 2021) |
| All-time low | $0.3019 (Feb 21, 2024) |
| 52-week high | $0.4406 |
| 52-week low | $0.3300 |
| Median price | $0.5387 |
| Average price | $0.6004 |
| Largest weekly change | +77.9% (Mar 20, 2024) |
| Weeks tracked | 309 |
| Tracking since | Nov 4, 2020 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Ingenus Pharmaceuticals LLC manufacturer profile
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Drug market
Leucovorin Calcium market comparison
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Therapeutic class
Folate Analog class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LEUCOVORIN CALCIUM 5 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LEUCOVORIN CALCIUM 5 MG TAB, manufactured by Ingenus Pharmaceuticals LLC, is $0.3300 per EA (NDC 50742018130), effective Sep 30, 2026.
How has the price of LEUCOVORIN CALCIUM 5 MG TAB changed over time?
Over the history we have for it, the NADAC for LEUCOVORIN CALCIUM 5 MG TAB has declined 62.8%. It has been tracked across 309 weekly CMS publications since Nov 4, 2020.
What are the highest and lowest recorded NADAC prices for LEUCOVORIN CALCIUM 5 MG TAB?
Since Nov 4, 2020, the NADAC for LEUCOVORIN CALCIUM 5 MG TAB has ranged from a low of $0.3019 (Feb 21, 2024) to a high of $0.8875 (Sep 15, 2021), with a median of $0.5387 per EA.
Are there cheaper alternatives to LEUCOVORIN CALCIUM 5 MG TAB?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LEUCOVORIN CALCIUM 5 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LEUCOVORIN CALCIUM 5 MG TAB?
LEUCOVORIN CALCIUM 5 MG TAB (NDC 50742018130) is labeled by Ingenus Pharmaceuticals LLC, and CMS classifies it as a generic product.