Product Information
CYCLOSPORINE MODIFIED 25 MG is a generic product labeled by Mayne Pharma, priced at $0.3184 per EA under NDC 51862045847. Its NADAC has been published 495 times since Sep 7, 2016.
FDA first approved this application on Dec 20, 2000. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Mayne PharmaNDC
51862045847
Classification
Generic
Dosage Form
CAPSULE, LIQUID FILLED
Route
ORAL
Effective Date
2/18/2026
Active Ingredients
CYCLOSPORINEApproval Type
Generic (ANDA)
FDA Application
ANDA065044FDA Approved
12/20/2000
TE Code
AB1
On Market Since
7/18/2016
Pharmacological Classes
Price Statistics
The NADAC for CYCLOSPORINE MODIFIED 25 MG has been published 495 times since Sep 7, 2016, and over the history we have for it it has declined 49.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3184 per EA |
|---|---|
| All-time high | $0.7006 (Sep 13, 2017) |
| All-time low | $0.3172 (Jan 21, 2026) |
| 52-week high | $0.3448 |
| 52-week low | $0.3172 |
| Median price | $0.5151 |
| Average price | $0.5207 |
| Largest weekly change | +53.8% (Aug 21, 2024) |
| Weeks tracked | 495 |
| Tracking since | Sep 7, 2016 |
1W
N/A
1M
N/A
3M
N/A
6M
0.0%
1Y
-7.7%
3Y
-33.0%
5Y
-51.4%
All
-49.7%
Last surveyed Feb 25, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 0% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of CYCLOSPORINE MODIFIED 25 MG?
The current National Average Drug Acquisition Cost (NADAC) for CYCLOSPORINE MODIFIED 25 MG, manufactured by Mayne Pharma, is $0.3184 per EA (NDC 51862045847), effective Feb 25, 2026.
How has the price of CYCLOSPORINE MODIFIED 25 MG changed over time?
Over the history we have for it, the NADAC for CYCLOSPORINE MODIFIED 25 MG has declined 49.7%. It has been tracked across 495 weekly CMS publications since Sep 7, 2016.
What are the highest and lowest recorded NADAC prices for CYCLOSPORINE MODIFIED 25 MG?
Since Sep 7, 2016, the NADAC for CYCLOSPORINE MODIFIED 25 MG has ranged from a low of $0.3172 (Jan 21, 2026) to a high of $0.7006 (Sep 13, 2017), with a median of $0.5151 per EA.
Are there cheaper alternatives to CYCLOSPORINE MODIFIED 25 MG?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CYCLOSPORINE MODIFIED 25 MG, is $0.3174 per EA — about 0% below CYCLOSPORINE MODIFIED 25 MG.
Who manufactures CYCLOSPORINE MODIFIED 25 MG?
CYCLOSPORINE MODIFIED 25 MG (NDC 51862045847) is labeled by Mayne Pharma, and CMS classifies it as a generic product.