Product Information

CYCLOSPORINE MODIFIED 25 MG is a generic product labeled by Apotex Corp., priced at $0.3174 per EA under NDC 60505463003. Its NADAC has been published 347 times since Jan 1, 2020.

FDA first approved this application on Jul 10, 2019. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CYCLOSPORINE MODIFIED 25 MG

Cyclosporine
$0.3174per EA

Strength

25 mg/1

Manufacturer

Apotex Corp.

NDC

60505463003

Classification

Generic

Dosage Form

CAPSULE, LIQUID FILLED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

CYCLOSPORINE

Approval Type

Generic (ANDA)

FDA Application

ANDA210721

FDA Approved

7/10/2019

TE Code

AB1

On Market Since

11/5/2019

Pharmacological Classes

Calcineurin Inhibitor Immunosuppressant
Calcineurin Inhibitors
Cytochrome P450 3A4 Inhibitors
P-Glycoprotein Inhibitors

Price Statistics

The NADAC for CYCLOSPORINE MODIFIED 25 MG has been published 347 times since Jan 1, 2020, and over the history we have for it it has declined 48.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.3174 per EA
All-time high$0.6629 (May 12, 2021)
All-time low$0.3100 (Apr 22, 2026)
52-week high$0.3448
52-week low$0.3100
Median price$0.4773
Average price$0.4747
Largest weekly change+53.8% (Aug 21, 2024)
Weeks tracked347
Tracking sinceJan 1, 2020

Price History

1W

-1.1%

1M

-1.1%

3M

+1.1%

6M

-0.3%

1Y

-8.0%

3Y

-33.3%

5Y

-51.6%

All

-48.1%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CYCLOSPORINE MODIFIED 25 MG?

The current National Average Drug Acquisition Cost (NADAC) for CYCLOSPORINE MODIFIED 25 MG, manufactured by Apotex Corp., is $0.3174 per EA (NDC 60505463003), effective Aug 19, 2026.

How has the price of CYCLOSPORINE MODIFIED 25 MG changed over time?

Over the history we have for it, the NADAC for CYCLOSPORINE MODIFIED 25 MG has declined 48.1%. It has been tracked across 347 weekly CMS publications since Jan 1, 2020.

What are the highest and lowest recorded NADAC prices for CYCLOSPORINE MODIFIED 25 MG?

Since Jan 1, 2020, the NADAC for CYCLOSPORINE MODIFIED 25 MG has ranged from a low of $0.3100 (Apr 22, 2026) to a high of $0.6629 (May 12, 2021), with a median of $0.4773 per EA.

Are there cheaper alternatives to CYCLOSPORINE MODIFIED 25 MG?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as CYCLOSPORINE MODIFIED 25 MG in a comparable dosage form, but none are currently priced below it.

Who manufactures CYCLOSPORINE MODIFIED 25 MG?

CYCLOSPORINE MODIFIED 25 MG (NDC 60505463003) is labeled by Apotex Corp., and CMS classifies it as a generic product.