Cyclosporine
41 NDCs across 14 manufacturers|31 Generic,10 Brand
Cyclosporine is used to treat rheumatoid arthritis, focal segmental glomerulosclerosis, systemic lupus erythematosus, myasthenia gravis and psoriasis, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Nov 14, 1983, and the first generic was approved Oct 29, 1999. FDA's Orange Book lists 33 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $1.7 billion on Cyclosporine across 2.3 million claims for 817,000 beneficiaries.
Cyclosporine is available as 41 NDCs from 14 manufacturers (31 generic, 10 brand), with NADAC prices from $0.32 to $15.34 per EA — the most expensive product costs about 48× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
41
31G / 10B
Manufacturers
14
competing in market
Price Spread
$0.32 – $15.34
per EA, 38 of 41 NDCs
7d Activity
avg -1.0% WoW · of 41 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
Manufacturer Breakdown
14 manufacturers producing CYCLOSPORINE(1 pricing outlier)
Frequently Asked Questions
What is Cyclosporine used to treat?
Cyclosporine is used to treat rheumatoid arthritis, focal segmental glomerulosclerosis, systemic lupus erythematosus, myasthenia gravis and psoriasis, per the National Library of Medicine's MED-RT classification.
When did Cyclosporine become available as a generic?
FDA approved the first generic Cyclosporine (ANDA) on Oct 29, 1999. The Orange Book currently lists 33 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Cyclosporine?
In 2024, Medicare Part D spent $1.7 billion on Cyclosporine across 2.3 million claims for 817,000 beneficiaries.
How many Cyclosporine products are on the market?
The Cyclosporine drug market contains 41 NDCs from 14 manufacturers — 31 generic and 10 brand products.
What is the price range for Cyclosporine?
NADAC reference prices for Cyclosporine range from $0.3174 to $15.3370 per EA — the most expensive product costs about 48× the cheapest. 3 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Is generic Cyclosporine cheaper than brand?
The average generic NADAC for Cyclosporine is $1.4789 per EA, versus $8.3036 for brand-labeled products — brand versions average about 5.6× the generic price.
Which manufacturers make Cyclosporine?
14 manufacturers list Cyclosporine in NADAC. Ranked by number of NDCs, the largest are Apotex Corp. (7), Teva Pharmaceuticals USA Inc. (6), Novartis Pharmaceuticals Corporation (4), Allergan, Inc. (3), AbbVie Inc. (3).
How has the price of Cyclosporine changed recently?
Over the past 7 days, 12 Cyclosporine NDCs rose and 18 fell, with a market-wide average change of -1.0%.