Product Information
SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.4960 per EA under NDC 53489014401. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Jul 2, 1987. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The Low Outlier badge above means this manufacturer's average price in the Spironolactone and Hydrochlorothiazide market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25; 25 mg/1; mg/1
Manufacturer
Sun Pharmaceutical Industries Inc.NDC
53489014401
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
HYDROCHLOROTHIAZIDE; SPIRONOLACTONEApproval Type
Generic (ANDA)
FDA Application
ANDA089534FDA Approved
7/2/1987
TE Code
AB
On Market Since
7/2/1987
Pharmacological Classes
Price Statistics
The NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 26.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4960 per EA |
|---|---|
| All-time high | $1.1475 (Dec 10, 2014) |
| All-time low | $0.3906 (Nov 20, 2024) |
| 52-week high | $0.5749 |
| 52-week low | $0.4960 |
| Median price | $0.7266 |
| Average price | $0.7554 |
| Largest weekly change | +37.7% (Aug 21, 2024) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 4% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
The current National Average Drug Acquisition Cost (NADAC) for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB, manufactured by Sun Pharmaceutical Industries Inc., is $0.4960 per EA (NDC 53489014401), effective Aug 19, 2026.
How has the price of SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB changed over time?
Over the history we have for it, the NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has declined 26.4%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
Since Nov 28, 2013, the NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has ranged from a low of $0.3906 (Nov 20, 2024) to a high of $1.1475 (Dec 10, 2014), with a median of $0.7266 per EA.
Are there cheaper alternatives to SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB, is $0.4757 per EA — about 4% below SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB.
Who manufactures SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?
SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB (NDC 53489014401) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.