Product Information

SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB is a generic product labeled by Sun Pharmaceutical Industries Inc., priced at $0.5414 per EA under NDC 53489014405. Its NADAC has been published 657 times since Nov 28, 2013.

The Low Outlier badge above means this manufacturer's average price in the Spironolactone and Hydrochlorothiazide market falls below Q1 − 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB

Spironolactone and Hydrochlorothiazide
$0.5414per EA
Low Outlier

Strength

25; 25 mg/1; mg/1

NDC

53489014405

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Last Updated

6/17/2026

Approval Type

Generic (ANDA)

FDA Application

ANDA089534

On Market Since

7/2/1987

Pharmacological Classes

Aldosterone Antagonist
Aldosterone Antagonists
Increased Diuresis
Thiazide Diuretic
Thiazides

Price Statistics

The NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 19.7%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5414 per EA
All-time high$1.1475 (Dec 10, 2014)
All-time low$0.3906 (Nov 20, 2024)
52-week high$0.5910
52-week low$0.5086
Median price$0.7270
Average price$0.7582
Largest weekly change+37.7% (Aug 21, 2024)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

+1.3%

3M

+6.4%

6M

+0.6%

1Y

-8.4%

3Y

-3.6%

5Y

-24.3%

All

-19.7%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 12% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?

The current National Average Drug Acquisition Cost (NADAC) for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB, manufactured by Sun Pharmaceutical Industries Inc., is $0.5414 per EA (NDC 53489014405), effective Jun 24, 2026.

How has the price of SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB changed over time?

Over the history we have for it, the NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has declined 19.7%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?

Since Nov 28, 2013, the NADAC for SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB has ranged from a low of $0.3906 (Nov 20, 2024) to a high of $1.1475 (Dec 10, 2014), with a median of $0.7270 per EA.

Are there cheaper alternatives to SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB, is $0.4757 per EA — about 12% below SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB.

Who manufactures SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB?

SPIRONOLACTONE-HYDROCHLOROTHIAZIDE 25-25 TAB (NDC 53489014405) is labeled by Sun Pharmaceutical Industries Inc., and CMS classifies it as a generic product.